한국식품영양과학회지 (Journal of the Korean Society of Food Science and Nutrition)
- Volume 34 Issue 4
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- Pages.466-475
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- 2005
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- 1226-3311(pISSN)
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- 2288-5978(eISSN)
DOI QR Code
인공 사육 동물 모델 시스템을 이용한 n-3 지방산 결핍이 쥐의 뇌, 망막, 간의 지방산 조성에 미치는 영향
Effect of n-3 Fatty Acid Deficiency on Fatty Acid Composition in Brain, Retina and Liver Using a Novel Artificial Rearing System
- 임선영 (한국해양대학교 해양환경생명과학부)
- Lim, Sun-Young (Division of Marine Environment & BioScience, Korea Maritime University)
- 발행 : 2005.04.01
초록
본 연구에서는 인공 사육 모델 시스템과 인공 쥐용 분유를 이용하여 출생 직후 12시간 이내에 엄마 쥐들로부터 신생 쥐를 분리하여 n-3 지방산 결핍분유와 n-3 지방산 적절분유로 3주 동안 사육한 후(이유기) 각각 장기들을 취하고 또한 성숙 쥐(15 wks)의 뇌, 망막, 간을 취하여 뇌 성장 발달 과정 동안 n-3지방산 결핍이 이들 장기들의 지방산조성 변화에 미치는 영향을 알아보고자 한다. 이유기와 성숙기 쥐의 뇌 지방산 조성은 n-3 지방산 적절군과 대조군과 비교했을 때, n-3지방산 결핍군의 경우 n-6지방산의 함량은 높았으나 (p<0.05), 총 monounsaturated 지방산과 총 n-3 지방산의 함량은 낮았고(p<0.05), 총 saturated 지방산의 경우는 변화가 없었다. 기대했듯이 뇌 DHA의 경우 n-3 지방산 결핍군은 n-3 지방산 적절군과 대조군에 비해 이유기 때
파일
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