Effects of conjugated linoleic acid and selenium on body composition and serum cholesterol concentration in broiler chickens

CLA와 selenium의 투여가 닭의 체구성과 혈중 콜레스테롤 수준에 미치는 영향

  • 전호진 (건국대학교 수의과대학) ;
  • 김진영 (건국대학교 수의과대학) ;
  • 임좌진 (건국대학교 수의과대학) ;
  • 이수한 (건국대학교 수의과대학) ;
  • 이병한 (건국대학교 수의과대학) ;
  • 정순욱 (건국대학교 수의과대학) ;
  • 박희명 (건국대학교 수의과대학) ;
  • 정병현 (건국대학교 수의과대학)
  • Accepted : 2005.08.17
  • Published : 2005.09.22

Abstract

The purpose of this study was to examine whether conjugated linoleic acid and selenium supplementation in broiler chicken diets would be effective, enhance indices of immune status and body weight, and modulate serum lipid concentration. Forty Hyline brown chickens, 1 weeks of age, were divided into 5 groups of 8 chickens. Chickens were fed the experimental diets supplemented with 1% CLA (conjugated linoleic acid; Group 1), 1% CLA + selenium (Group 2), 1% safflower-seed-oil as LA (Group 3), 1% safflower-seed-oil as LA + selenium (Group 4) or nothing (Control) for 4 weeks. After 4 weeks, serum, liver, spleen and abdominal fat were taken. Measurement of total immunoglobulin were executed using sandwich ELISA. Weight ratio of liver to body showed that the group fed with CLA were significantly higher than the group fed with CLA + selenium. Weight ratios of spleen and fat to body showed no significantly differences. In concentrations of serum total cholesterol and HDL-cholesterol, the group fed with CLA showed significantly higher values than that fed with CLA + selenium. In concentrations of serum triglyceride and LDL-cholesterol there were no significantly differences between the treatment groups. In conclusion, supplementation of CLA with selenium protected hepatomegaly and reduced level of serum total cholesterol and HDL-cholestererol in chickens.

Acknowledgement

Supported by : 건국대학교

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