DOI QR코드

DOI QR Code

Polyphenol Contents and Antioxidant Activity of Lepista nuda

민자주방망이버섯의 폴리페놀 함량과 항산화활성

  • Lee, Yang-Suk (Dept. of Herbal Biotechnology, Daegu Haany University) ;
  • Joo, Eun-Young (Dept. of Herbal Biotechnology, Daegu Haany University) ;
  • Kim, Nam-Woo (Dept. of Herbal Biotechnology, Daegu Haany University)
  • 이양숙 (대구한의대학교 한방생약자원학과) ;
  • 주은영 (대구한의대학교 한방생약자원학과) ;
  • 김남우 (대구한의대학교 한방생약자원학과)
  • Published : 2006.12.29

Abstract

This study analyzed the contents of vitamin C, polyphenol compounds, and evaluated the inhibitory activities against xanthine oxidase and tyrosinase of Lepista nuda extract prepared by the reflux and microwave-assisted methods. The vitamin C content of the fresh L. nude was $9.92{\pm}0.02$ mg/100 g. The content of phenolic compounds in the fresh L. nuda was $1.87{\pm}0.02\;mg/g$. The ethanol extracts prepared by reflux method and microwave-assisted method showed the highest phenol contents of $12.06{\pm}0.12\;mg/g\;and\;11.84{\pm}0.17\;mg/g$, respectively. The inhibitory rates on xanthine oxidase and tyrosinase of ethanol extracts prepared by the microwave assisted method showed the highest value of 99.78% and 30.30% at the concentration of $3,000{\mu}g/mL$. The inhibitory activities on xanthine oxidase and tyrosinase were increased depending on the extract concentration.

References

  1. Culter RG. 1984. Antioxidants aging and longevity. In Free Radicals in Biology. Pryor WA, ed. Academic Press, New York, USA. Vol 6, p 371-423
  2. Sung JM, Yoo YB, Cha DY. 1998. Mushroom science. Kor-Hak Publish, Seoul, Korea
  3. Jeong OJ, Yoon HS, Min YK. 2001. Aroma characteristics of neungee. Korean J Food Sci Technol 33: 307-312
  4. Ma SJ. 1983. Effects of the substances extracted from dried mushroom by several organic solvents on the stability of fat. Korean J Food Sci Technol 15: 150-154
  5. Chung SY, Kim SH, Kim HS, Kang JS, Cheong HS, Kim GJ, Kim HJ. 1990. Effects of water soluble extract of Ganoderma lucidum, kale juice and sodium dextrothyroxine on hormone and lipid metabolism in hypercholesterolemic rats 1. Concentrations of triodothyronine, thyroxine, blood sugar and lipid composition in serum. J Korean Soc Food Sci Nutr 19: 381-386
  6. Park SY, Kim JW. 1992. Screening and isolation of the antitumor agents from medicinal plants (I). Kor J Pharmacogn 23: 264-267
  7. Lee BW, Lee MS, Park KM, Kim CH, Ahn PU, Choi CU. 1992. Anticancer activities of the extract from the mycelia of Coriolus versicolor. Kor J Appl Microbiol Biotechnol 20: 311-315
  8. Park WH. 1998. Studies on inorganic components of Korean wild edible mushrooms-trace mineral elements of Armillariella mella, Hygrophorous russula, Armillariella tabescens, Lepista nuda, Lepista sordida, Hygrocybe conica. Korean J Mycol 21: 273-278
  9. Lee YS, Han JY, Joo EY, Shin SR, Kim NW. 2004. Study on the anti-tumor effects of extracts from Lepista nuda mushroom. J Korean Soc Food Sci Nutr 34: 317-322 https://doi.org/10.5051/jkape.2004.34.2.317
  10. Kim JH, Yoo KH, Kim YS, Seok SJ, Kim YS. 1998. The screening of fibrinolytic activities of extracts from mushrooms in mt. Chiak. Korean J Mycol 26: 589-593
  11. Lee YS, Park DC, Joo EY, Shin SR, Kim NW. 2005. Study on the antioxidant activity of the extracts from the Lepista nuda. J Korean Soc Food Sci Nutr 34: 942-917 https://doi.org/10.3746/jkfn.2005.34.7.942
  12. Hatano T. 1995. Constituents of natural medicines with scavenging effect on active oxygen species-tannins and related polyphenols. Natural Medicine 49: 357-363
  13. Kitahara K, Matsumoto Y, Ueda H, Ueoka R. 1992. A remarkable antioxidation effect of natural phenol derivatives on the autoxidation of irradiated methyl linoleate. Chem Pharm Bull 40: 2208-2209 https://doi.org/10.1248/cpb.40.2208
  14. Chan KM, Decher EA, Means WJ. 1993. Extraction and activity of carmosine, a naturally occurring antioxidant in beef muscle. J Food Sci 58: 1-4 https://doi.org/10.1111/j.1365-2621.1993.tb03199.x
  15. Kartner N, Ling V. 1989. Multidrug resistance in cancer. Sci Am 260: 44-51 https://doi.org/10.1038/scientificamerican0389-44
  16. Azuma K, Nakayama M, Koshika M, Lppoushi K, Yamaguchi Y, Kohata K, Yamaguchi Y, Ito H, Higashio H. 1999. Phenolic antioxidants from the leaves of Corchorus olitorius L. J Agric Food Chem 47: 3963-3966 https://doi.org/10.1021/jf990347p
  17. Ham SS, Hong JK, Lee JH. 1997. Antimutagenic effects of juices from edible Korean wild herbs. J Food Sci Nutr 2: 155-161
  18. Labuza TP. 1971. Kinetic of lipid oxidation in foods. CRC Crit Rev Food Technol 2: 335-405
  19. Kwon TD, Choi SW, Lee SJ, Chung KW, Lee SC. 2001. Effects of polyphenol or vitamin C ingestion on antioxidative activity during exercise in rats. Kor J Physical Education 3: 891-899
  20. Byers T, Perry G. 1991. Dietary carotenes, vitamin C and vitamin E as protective antioxidants in human cancers. Ann Rev Nutr 12: 139-159
  21. Diplock AT. 1991. Antioxidants nutrients and disease prevention. Am J Clin Nutr 53: 1895-1935
  22. Frei B. 1991. Ascorbic acid protects lipids in human plasma and low density lipoprotein against oxidative damage. Am J Clin Nutr 54: 1113-1115 https://doi.org/10.1093/ajcn/54.6.1113s
  23. Chan D, Lamande SR, Cole WG, Bateman JF. 1990. Regulation of procollagen synthesis and processing during ascorbate-induced extracellular matrix accumulation in vitro. J Biochem 269: 175-179 https://doi.org/10.1042/bj2690175
  24. Kim M, Ostuka M, Ui R, Kirata T, Arakawa N. 1994. The distribution of ascorbic acid and dehydroascorbic acid during tissue regeneration in wounded dorsal skin of guinea pigs. Internat J Vit Nutr Res 64: 56-59
  25. Murad S, Sivarajab A, Pinnell SR. 1981. Regulation of prolyl and lysyl hydroxylase activities in cultured human skin fibroblasts by ascorbic acid. Biochem Biophys Res Commun 101: 868-875 https://doi.org/10.1016/0006-291X(81)91830-1
  26. Yu R, Kirata T, Kim M, Arakawa N. 1991. The behavior of L-ascorbic acid in the healing process of dorsal wounds in guinea pigs. J Nutr Sci Vitaminol 37: 207-211 https://doi.org/10.3177/jnsv.37.207
  27. Murad S, Tajima S, Johnson GR, Sivarajah A, Pinnell SR. 1981. Collagen synthesis in cultured human skin fibrlblasts: effect of ascorbic and its analogs. J Invest Dermatol 81: 158-162
  28. Peterkofsky B. 1972. The effect of ascorbic acid on collagen polypeptide synthesis and proline hydroxylation during the growth of cultured fibrinoblasts. Arch Biochem Biophys 152: 318-328 https://doi.org/10.1016/0003-9861(72)90221-4
  29. Kim MH. 1998. The effect of ascorbic acid on the enzyme reaction in pyridinoline formation during soluble collagen maturation. J Korean Soc Food Sci Nutr 27: 305-312
  30. Hatano T, Yasuhara T, Fukuda T, Noro T, Okuda T. 1989. Phenolic constituents of licorce. II. Structures of licopyranocoumarin, licoarylcoumarin and glisoflavone, and inhibitory effects of locorice phenolics on xanthine oxidase. Chem Phar Bull 11: 3005-3009
  31. Storch I, Ferber E. 1988. Detergent-amplified chemiluminescence of lucigenin for determination of superoxide amino production by NADPH oxidase and xanthine oxidase. Anal Biochem 169: 262-267 https://doi.org/10.1016/0003-2697(88)90283-7
  32. Wyngaarden JB, Holmes EW Jr. 1977. Molecular nature of enzyme regulation in purine biosynthesis. Ciba Found Symp 48: 43-64
  33. Bell AA, Weeler MH. 1986. Biosynthesis and melanin. Ann Rev Phytophathol 24: 411-451 https://doi.org/10.1146/annurev.py.24.090186.002211
  34. Iyengar R, McEvily AJ. 1992. Anti-browning agents: alternative to the use of sulfites in foods. Trends Food Sci Technol 3: 60-63 https://doi.org/10.1016/0924-2244(92)90131-F
  35. Lee SH, Kim NW, Shin SR. 2003. Studies on the nutritional components of mushroom (Sarcodon aspratus). Korean J Food Preserv 10: 65-69
  36. Jung SW, Lee NK, Kim SJ, Han DS. 1995. Screening of tyrosinase inhibitor from plants. Korean J Food Sci Technol 27: 891-896
  37. Tomita K, Oda N, Kamel M, Miyakim T, Oki T. 1990. A new screening method for melanin biosynthesis inhibitors using Streptomyces bikiniensis. J Antibiotics 12: 1602- 1605
  38. AOAC. 2005. Official method of analysis. 18th ed. Association of official analytical chemists, Washington DC, USA. Vol 45, p 21-22
  39. Swain T, Hillis WE, Ortega M. 1959. Phenolic constituents of Ptunus domestica. I. Quantitative analysis of phenolic constituents. J Sci Food Agric 10: 83-88
  40. Stirpe F, Corte ED. 1969 The regulation of rat liver xanthine oxidase. J Biol Chem 244: 3855-3861
  41. Yagi A, Kanbara T, Morinobu N. 1986. The effect of tyrosinase inhibition for aloe. Planta Medica 3981: 517-519
  42. Hong KH, Kim BY, Kim HK. 2004. Analysis of nutritional components in Pleurotus ferulea. Korean J Food Sci Technol 36: 563-567
  43. Kwon HH, Kim IB, Kim SH, Kim ES, Kim JH, Yu JY. 1984. Studies on the nutritive value of Korean foods (X VI). J Korean Soc Food Nutr 13: 334-338
  44. Kim YH, Oh SH. 1987. Analysis of general composition, polyphenols and amino acids in Sarcodon aspratus. J Choonbok Univ Arg 18: 44-50
  45. Lee JH, Lee SR. 1994. Analysis of phenolic substances content of Korea plant foods. Korean J Food Sci Technol 26: 310-316
  46. Moon JS, Kim SJ, Par YM, Hwang IS, Kim EY, Park JW, Park IB, Kim SW, Kang WG, Park YK, Jung ST. 2004. Antimicrobial effect of methanol extracts from some medicinal herbs and content of phenolic compounds. Korean J Food Preserv 11: 207-213
  47. Ann BJ, Lee JT. 2002. Studies on biological activity from extract of Crataegi fructus. Kor J Herbology 17: 29-38
  48. Lee JT, Ann BJ. 2002. Detection of physical activity of Salicornia herbacea. Kor J Herbology 17: 61-69
  49. Jung SH, Jo WA, Son JH, Choi SE, Park CI, Lee IC, An BJ, Son AR, Kim SK, Kim YS, Lee JT. 2005. A study on the application of cosmetic materials and the physiological activities of Forsythia koreana Nakai. Kor J Herbology 20: 61-68
  50. Kim HK, Choi YJ, Jeong SW, Kim KH. 2002. Functional activities of microwave-assisted extracts from Lyophy ulmarium. Korean J Food Preserv 9: 385-390
  51. Park YH, Chang SK. 1997. Screening of inhibitory effect of edible mushrooms on tyrosinase and isolation of active component. J Fd Hyg Safety 12: 195-199

Cited by

  1. Antioxidative Activities and Inhibition of DNA Damage of Ethylacetate Fraction from Sophorae Flos and Sophorae fructus vol.30, pp.2, 2015, https://doi.org/10.6116/kjh.2015.30.2.31
  2. Physiological activitive of Grifola frondosa by log cultivation and bottle cultivation vol.13, pp.3, 2015, https://doi.org/10.14480/JM.2015.13.3.185
  3. Antioxidant activities and inhibitory effects on oxidative DNA damage of leaf fromZelkova serratawith ethyl acetate fractions and hot water extracts vol.59, pp.3, 2016, https://doi.org/10.3839/jabc.2016.044
  4. Effect of Cheongungdajosan-gamibang on oxidative damage and inflammation vol.29, pp.4, 2014, https://doi.org/10.6116/kjh.2014.29.4.53
  5. Comparison of Antioxidant Activities of Pileus and Stipe from White Beech Mushrooms (Hypsizygus marmoreus) vol.26, pp.8, 2016, https://doi.org/10.5352/JLS.2016.26.8.928
  6. Antioxidant Activities of Pleurotus cornucopiae Extracts by Extraction Conditions vol.43, pp.6, 2014, https://doi.org/10.3746/jkfn.2014.43.6.836
  7. Total Phenol Contents and DPPH Radical Scavenging Activity of Entomopathogenic Fungi vol.48, pp.3, 2009, https://doi.org/10.5656/KSAE.2009.48.3.377
  8. Enhancement of Antioxidant Activities of Curcuma longa Leaves by Ultra High Pressure Extraction vol.22, pp.2, 2014, https://doi.org/10.7783/KJMCS.2014.22.2.121
  9. Antioxidant Activity and Inhibitory Effect on Oxidative DNA Damage of Ethyl Acetate Fractions Extracted from Cone of Red Pine (Pinus densiflora) vol.29, pp.2, 2016, https://doi.org/10.7732/kjpr.2016.29.2.163
  10. root vol.61, pp.2, 2018, https://doi.org/10.3839/jabc.2018.016