Application of Ionic Liquids as Mobile Phase Modifier in HPLC

  • Polyakova Yulia (Center for Advanced Bioseparation Technology and Department of Chemical Engineering, Inha University) ;
  • Koo Yoon-Mo (Center for Advanced Bioseparation Technology and Department of Chemical Engineering, Inha University) ;
  • Row Kyung-Ho (Center for Advanced Bioseparation Technology and Department of Chemical Engineering, Inha University)
  • Published : 2006.01.01


Ionic liquids are receiving an upsurge of interest as 'green' solvents; primarily as replacements for conventional media in chemical processes. Although ionic liquids are rather 'young' modifier, their great potential in high-performance liquids chromatography (HPLC) has already been demonstrated. This review presents an overview of the applications of ionic liquids as mobile phase modifiers in HPLC.


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