Effects of Biocom as a Replacement of Glutamine on Performance and Blood Biochemical Indexes of Early Weaned Piglets

  • Zhou, R.Y. (Key Laboratory of Swine Breeding and Genetics of Agricultural Ministry, College of Animal Science and Technology Huazhong Agricultural University) ;
  • Peng, J. (Key Laboratory of Swine Breeding and Genetics of Agricultural Ministry, College of Animal Science and Technology Huazhong Agricultural University) ;
  • Liu, Z.L. (Key Laboratory of Swine Breeding and Genetics of Agricultural Ministry, College of Animal Science and Technology Huazhong Agricultural University) ;
  • Fang, Z.F. (Key Laboratory of Swine Breeding and Genetics of Agricultural Ministry, College of Animal Science and Technology Huazhong Agricultural University)
  • Received : 2005.08.12
  • Accepted : 2005.12.13
  • Published : 2006.06.01


The objective of this study was to evaluate Biocom (a protein source containing a high level of glutamine and alanyl-glutamine) as a replacement for glutamine (Gln) in nursery pig diets. Forty-two pigs (fourteen pigs per treatment) weaned at 28 d of age were used in a 28-d performance trial using three dietary treatments: control (no Gln), control supplemented with Gln or Biocom. The control diet was composed of corn, soybean meal, whey and fish meal. Individual body weight, pen feed disappearance and diarrhea were monitored. On d 0, 2, 7 and 14 postweaning, respectively, five pigs per treatment were selected and bled from the anterior vena cava to obtain five replicate samples of blood on each dietary treatment for determination of blood biochemical index. Dietary supplementation of Gln and Biocom did not influence performance, plasma Gln and total serum protein concentration (p>0.05). However, the addition of Gln and Biocom could prevent serum urea nitrogen and serum cortisol from increasing on d 2 postweaning (p<0.05). There were no significant differences (p>0.05) in any of the examined parameters between Gln- and Biocom-supplemented diets. In conclusion, dietary Gln did not influence the performance of early-weaned piglets owing to the complex diet containing whey, but could prevent the increase of serum urea and cortisol. Biocom could be used as a replacement for free pure Gln without any negative effect on early-weaned piglets.


Glutamine;Alanyl-glutamine;Biocom;Performance;Biochemical Indexes;Weanling Pigs


Grant : Glutamine in Immunologic Responses in Early Weaned Piglets

Supported by : Department of Science and Technology of Hubei Province


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