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The Effects of Levan on Blood Lipids and the Absorption of Calcium in Rats Fed a Low Calcium Diet

레반의 혈장지질 감소와 칼슘흡수율 증가 효과

  • No, Jung-Ran (Dept. of Food and Nutrition, Chungnam National University) ;
  • Park, Sun-Young (Dept. of Food and Nutrition, Chungnam National University) ;
  • Kim, Mi-Kyoung (DMJ Biotechnology Research Institute, DMJ Biotech Corp.) ;
  • Jo, Han-Young (DMJ Biotechnology Research Institute, DMJ Biotech Corp.) ;
  • Lee, In-Young (DMJ Biotechnology Research Institute, DMJ Biotech Corp.) ;
  • Ly, Sun-Yung (Dept. of Food and Nutrition, Chungnam National University)
  • Published : 2007.01.31

Abstract

Levan, the fructose polymer is an indigestible carbohydrate regularly consumed by humans. Its physiological functions, in terms of hypocholesterolemic effect and calcium metabolism, have not been well documented. The objective of this study was to investigate the effects of levan on blood lipids and the calcium absorption ratio in rats fed a 0.1% low calcium diet. Thirty rats were divided into three groups and fed a 0.1% low calcium diet (control) or low calcium diets containing either 2.5% levan or 5% levan for eight weeks. The blood lipid and biomarkers relevant to Ca metabolism (urinary Ca and hydroxyproline), the femoral weight and the Ca contents were determined. The body weight gains were lower in the 5% levan group than the control group. Plasma concentrations of triacylglycerol and LDL-cholesterol decreased in the 5% levan group, compared to the control group, but the atherogenic indice were not affected. Blood alkaline phosphatase activity, Ca and urinary hydroxyproline excretion levels were not different in the three groups. The net calcium absorption in rats fed a 5% levan diet was greater than rats fed the control diet, while the femoral weights and Ca contents were not significantly different in the three groups. We concluded that a 5% levan diet could both enhance the calcium absorption and improve the lipid profiles in rats fed a low calcium diet.

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