Risk assessment of the potential for a classical swine fever outbreak in Korea based on a herd immunity

  • Lee, Changhee (College of National Sciences, Kyungpook National University) ;
  • Yoon, Hachung (National Veterinary Research and Quarantine Services) ;
  • Park, Choi-Kyu (National Veterinary Research and Quarantine Services)
  • Accepted : 2007.11.30
  • Published : 2007.12.30

Abstract

The risk of an outbreak of classical swine fever (CSF) was evaluated in relation to the vaccination and seroprevalence of antibodies. Blood samples were collected from 60 piggeries throughout Korea and information regarding CSF vaccination habits was also obtained via in-person interviews with pig farmers. The results of the survey indicated that 51 out of 60 farms were regularly performing CSF vaccinations in reproductive herds. Farmers preferred to vaccinate their reproductive pigs before weaning (41 farms) than on (9 farms) or after weaning (1 farm). In growing herds, however, double vaccinations as recommended were implemented for only 40 farms (66.7%) and vaccine schedules were identified as being frequently ignored. Moreover, many farms (18/40) were found to vaccinate earlier or later than the recommended time. According to antibody seroprevalence levels, only 36 farms (60%) were considered to be safe regarding potential risk for a CSF outbreak. Among the remaining pig farms, 6 were at low-risk (10%), 12 were at medium-risk (20%), and another 6 were at high-risk (10%). Antibody levels were found to be consistent with vaccination status obtained from personal interview surveys. Our findings demonstrate the importance of vaccinations regarding the prevention of a CSF outbreak, suggesting that vaccinations must be promoted toward pig raisers and practitioners.

References

  1. de Smit AJ. Laboratory diagnosis, epizootiology, and efficacy of marker vaccines in classical swine fever: a review. Vet Q 2000, 22, 182-188 https://doi.org/10.1080/01652176.2000.9695054
  2. Edwards S, Fukusho A, Lefevre PC, Lipowski A, Pejsak Z, Roehe P, Westergaard J. Classical swine fever: the global situation. Vet Microbiol 2000, 73, 103-119 https://doi.org/10.1016/S0378-1135(00)00138-3
  3. Kang BJ, Kwon HJ, Lee HS. Studies on the application of LOM hog cholera vaccine to domestic swine in Korea. Res Rept RDA (L & V) 1967,10,85-93
  4. Kim J, Chung HK, Chae C. Association of porcine circovirus 2 with porcine respiratory disease complex. Vet J 2003, 166, 251-256 https://doi.org/10.1016/S1090-0233(02)00257-5
  5. Lin M, Trottier E, Mallory M. Enzyme-linked immunosorbent assay based on a chimeric antigen bearing antigenic regions of structural proteins $E^{ms}$ and E2 for serodiagnosis of classical swine fever virus infection. Clin Diagn Lab Immunol 2005, 12, 877-881
  6. Meyers G, Thiel HJ. Molecular characterization of pestiviruses. Adv Virus Res 1996, 47, 53-118 https://doi.org/10.1016/S0065-3527(08)60734-4
  7. Moennig V. Introduction to classical swine fever: virus, disease and control policy. Vet Microbiol 2000, 73, 93-102 https://doi.org/10.1016/S0378-1135(00)00137-1
  8. Ozawa Y, Makino S, Park JY, Chang JH, Kim JH, An SH. A review of recent unexpected animal disease events in Japan and Korea and the follow-up action taken. Rev Sci Tech 2006, 25, 125-135
  9. Park CK, Song JY, Wee SH, Lee ES, Yoon H, Moon OK, Choi EJ, Nam HM. Epidemiological characteristics of 2002 outbreak of classical swine fever in Korea. Korean J Vet Res 2006, 46, 107-117
  10. Park CK, Lee ES, Yoon H, Wee SH, Song JY, Moon OK, Choi EJ, Kim HS, Lee, JH, An SH. Descriptive epidemiology of nationwide spread of 2003 classical swine fever epidemic in Korea. Korean J Vet Res 2006, 46, 197-206
  11. Paton DJ, Mcgoldrick A, Greiser-Wilke I, Parchariyanon S, Song JY, Liou PP, Stadejek T, Lowings JP, Bjorklund H, Belak S. Genetic typing of classical swine fever virus. Vet Microbiol 2000, 73, 137-157 https://doi.org/10.1016/S0378-1135(00)00141-3
  12. Terpstra C, Bloemraad M, Gielkens AL. The neutralizing peroxidase-linked assay for detection of antibody against swine fever virus. Vet Microbiol 1984, 9, 113-120 https://doi.org/10.1016/0378-1135(84)90026-9
  13. van Oirschot JT. Vaccinology of classical swine fever: from lab to field. Vet Microbiol 2003, 96, 367-384 https://doi.org/10.1016/j.vetmic.2003.09.008
  14. Wee SH, Park CK, Jeong JM, Kim CH, Hwang IJ, Kim SJ, Yoon H, Lee ES, Nam HM, Park JY, Moon OK. Outbreaks of classical swine fever in the Republic of Korea in 2003. Vet Rec 2005, 157, 113-115 https://doi.org/10.1136/vr.157.4.113
  15. Wengler G, Bradly DW, Collett MS, Heinz FX, Schlesinger RW, Strauss JH. Flaviviridae. In: Murphy FA, Fauquet CM, Bishop DHL, Ghabrial SA, Jarvis AW, Martelli GP, Mayo MA, Summers MD (eds.). VIrus Taxonomy. Sixth Report of the International Committee on Taxonomy of Viruses. pp. 415-427, Springer Verlag, New York, 1995