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Relationship between HsCRP and Pulse Transit Time

HsCRP와 맥파전달시간에 대한 연구

  • Kim, Yun-Jin (Dept. of Family Medicine, School Medicine, Pusan National University Hospital) ;
  • Min, Hong-Gi (Dept. of Family Medicine, School Medicine, Pusan National University Hospital) ;
  • Kim, Young-Joo (Dept. of Family Medicine, School Medicine, Pusan National University Hospital) ;
  • Jeon, Ah-Young (Dept. of Biomedical-Engineering, School of Medicine, Pusan National University Hospital) ;
  • Jeon, Gye-Rok (Dept. of Biomedical-Engineering, School of Medicine, Pusan National University Hospital) ;
  • Ye, Soo-Young (BK21 Medical Science Education Center, School of Medicine, Pusan National University)
  • 김윤진 (부산대학교 의학전문대학원 가정의학교실) ;
  • 민홍기 (부산대학교 의학전문대학원 가정의학교실) ;
  • 김영주 (부산대학교 의학전문대학원 가정의학교실) ;
  • 전아영 (부산대학교 의학전문대학교 의공학교실) ;
  • 전계록 (부산대학교 의학전문대학교 의공학교실) ;
  • 예수영 (부산대학교 의학전문대학원 BK2l 고급의료인력양성사업단)
  • Published : 2007.02.28

Abstract

The purpose of this study is to evaluate the relationship between high sensitive C-reactive protein (hsCRP) and pulse transit time (PPT). Apparently healthy 233 subjects had been enrolled in the health promotion center of the Pusan National University Hospital from Jan. 29 to Feb. 26, 2004. They had no previous history of diabetes, hypertension and hyperlipidemia. Subjects were categorized according to tertiles of hsCRP level [Group 1: first tertile $(0.01\;{\sim}\;0.02\;mg/dl)$, Group 2: second tertile $(0.03\;{\sim}\;0.05\;mg/dl)$, Group 3: third tertile $(0.06\;{\sim}\;0.12\;mg/dl)$, and Group 4: Fourth tertile $(0.13\;{\sim}\;16.8\;mg/dl)$]. PTT body mass index (BMI), total cholesterol (T-C), LDL-cholesterol(LDL-C), blood sugar (BS), systolic blood pressure (sBP) and diastolic blood pressure (dBP) were significantly different among hsCRP groups (p<0.05). HsCRP is positively related with BMI, tryglyceride (TG), LDL, sBP and dBP (p<0.05), and negatively related with PTT and HDL-cholesterol (HDL-C) (p<0.05). PTT is significantly negatively related with hsCRP, T-C, TG, LDL-C, BS, dBP and sBP (p<0.05). The hsCRP and PTT were related before controlling BMI, T-C, LDL-C, sBP, and dBP, but not related after conkolling. The relationship between hsCRP and PTT depends on cardiovascular disease risk factors.

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