Pharmacetical Characteristics and Analysis of Garlic Extract

마늘 추출물의 약리적 특성 및 분석

  • Sung, Ki-Chun (Department of Chemical Engineering, Daejin University)
  • 성기천 (대진대학교 공과대학 화학공학과)
  • Published : 2007.09.30


From the experiment result on pharmacetical characteristics and analysis of Garlic extract, some conclusions were obtained as follows. From the results on extract experiment of Garlic, extraction ratio was about 6.0%, and after dried with dry oven from Garlic extract, it obtained about 50%-Garlic extract of solid state. From results on antimicrobial experiment of Garlic extract, number of staphylococcus and fungus in microbe decreased more and more according to time passage. This phenomenon showed that Garlic extract keeps antimicrobial effect. From results on antioxidation experiment of Garlic extract, DPPH scavenging activity of free radical showed that Garlic extract appears more remarkable reduction ability than reference samples. This phenomenon means that antioxidation of Garlic extract appears higher than Vitamin-C and BHA. From results on instrument analysis, inorganic components of K, Na, Ca, Si, Mg, Zn etcs from Garlic extract were detected with ICP/OES and the fatty and aromatic components of trimethyl sulfide, diallyl disulfide, diallyl trisulfide, 2-mercaptobenzothiazole etcs from Garlic extract were detected with GC/MS.


  1. B. Reghavan and K. O. Abraham, J. Scient. Ind. Res., 42, 401 (1983)
  2. L. D. Lawson and R. Bauer, Phytomedicines of Europe The Chemistry & Biological Activity, ACS Symposium Series, 691, p.p 176-209 (1998)
  3. D. B. Shin, H. M. Seong, J. H. Kim, and Y. C. Lee, Flaver Composition of Garlic from Different Area, Korean J. Food Sci. Technol., 31(2), p.p 293-300 (1999)
  4. K. N. Shashikanth, S. C. Basappa, and V. S. Murthy, Studies on the Antimicrobial and Stimulatory Factor of Garlic, J. Food Sci. Technol., 118, 44 (1981)
  5. M. H. Cheng and T. C. Jung, Effect of Allithiamine on Sacroma-180 Tumor, Tai-wan 1 Husuch Hui Tsa Chief., 80(4), p.p 385-392 (1981)
  6. K. K. Sharma, Effect of Onion and Garlic on Serum Cholesterol on Normal Subjects, Mediscope, 22(7), 134 (1979)
  7. R. C. Jain and C. R. Vyas, Garlic in Alloxan-Induced Diabetic Rabbits, Am J. Clim. Nuir., 28(7), p.p 681-684 (1975)
  8. L. Walton, M. Herbold, C. C. Lindegren, Bactericidal Effects of Vapors from Crushed Garlic, Food Res., 1, p.p 163-169 (1936)
  9. E. Block, The Chemistry of Garlic and Onion, Sci. Am., 252, p.p 94-99 (1985)
  10. C. J. Cavalli to and J. H. Bailey, Allicin ; The Antibacterial principle of Allium Sativum L., Isolation : Physical Properties and Antimicrobial Action, J. Amer. Chem. Soc., 66, p.p 1950-1951 (1944)
  11. A. Stoll and E. Seebeck, Chemical Investigation of Allicin, The Specific Principle of Garlic, Adv. Enzvmol., 11, p.p 377-400 (1951)
  12. E, Block, S. Naganathan, D. Putman, and S. H. Zhao, Allium Chemistry : HPLC Analysis of Thiosulfinates from Onion, Garlic, Wild Garlic, Leek, Scallion, Shallot, Elephant Garlic, Chive and Chinese Chive, J. Agric. Food Chem., 40, p.p 2418-2430 (1992)
  13. T. J. Yu and C. M. Mu, Stability of Allicin in Garlic Juice, J. Food Sci., 54, p.p 977-980 (1989)
  14. E. A. Ogawa, D. J. Hill and D. J. Maslin, Activities of Garlic Oil, Garlic Powder, and Their Diallyl Constituents against Helicobacter, Pylori. Appl. Environ Microbial; 66, p.p 2269-2273 (2000)
  15. M. S. Blois, Nature, 181, p.p 1199-1200 (1958)
  16. G. S. Lee, Practice of Microbiology, Bureau of Publication, 329 (1992)