Antioxidative Activity of Gynostemma pentaphyllum Makino Extracts

덩굴차(Gynostemma pentaphyllum Makino) 추출물의 항산화 효과

  • Hyun, Sun-Hee (College of Pharmacy, Kyunghee University) ;
  • Lee, Jong-Suk (College of Pharmacy, Yeungnam University) ;
  • Lee, Kwang-Bae (Department of Clinical Pathology, Daegu Health College) ;
  • Lee, Jae-Sung (Food Technology and Food Service Industry, Yeungnam University)
  • Published : 2007.08.31


This study was carried out to examine the antioxidant activity of Gynostemma pentaphyllum Makino. Using the DPPH method, we found that free radical scavenging activity was strong in all the fractions except the water fraction of the water extract (GPW) and ethanol extract (GPE) of G pentaphyllum Makino. Pseudo-SOD activity was highest in the diethyl ether fraction of the ethanol extract, while the other fractions of the ethanol and water extracts were lower. For xanthine oxidase inlribition activity, the diethyl ether fraction and butanol fraction of GPW, and the diethyl ether fraction and butanol fraction of GPE, showed activities over 80%. Nitrite scavenging ability was strong (over 60%) in all the GPW and GPE fractions. The diethyl ether fraction and butanol fraction of GPW had more effective nitrite scavenging abilities than the other extract fractions. These results suggest that the extracts of G pentaphyllum Makino can be used as a functional material in a tea or drink.


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