Immunomodulatory characteristics of Streptococcus parauberis isolated from infected olive flounder, Paralichthys olivaceus

넙치, Paralichthys olivaceus 병어에서 분리된 Streptococcus parauberis의 면역 저항 특성

  • Hwang, Seong-Don (Department of Aquatic Life Medicine, Pukyong National University) ;
  • Woo, Sung-Ho (Department of Aquatic Life Medicine, Pukyong National University) ;
  • Kim, Su-Hyeon (Department of Aquatic Life Medicine, Pukyong National University) ;
  • Ha, Su-Jin (Department of Aquatic Life Medicine, Pukyong National University) ;
  • Jung, Young-Eun (Department of Aquatic Life Medicine, Pukyong National University) ;
  • Park, Soo-Il (Department of Aquatic Life Medicine, Pukyong National University)
  • 황성돈 (부경대학교 수산생명의학과) ;
  • 우승호 (부경대학교 수산생명의학과) ;
  • 김수현 (부경대학교 수산생명의학과) ;
  • 하수진 (부경대학교 수산생명의학과) ;
  • 정영은 (부경대학교 수산생명의학과) ;
  • 박수일 (부경대학교 수산생명의학과)
  • Published : 20081200


Streptococcal diseases are known as serious problems in fresh water and marine fish culture industry worldwide. Recently, the importance of the infection of Streptococcus parauberis has been increased among the streptococcicosis since severe outbreaks in cultured olive flounder (Paralichthys olivaceus) were recorded in Korea. The aims of the present study were to investigate immunomodulatory differences between S. parauberis and S. iniae. In this study, S. parauberis isolated from diseased olive flounder was investigated on the characteristics of morphological and immune responses. Immune response of the fish to the pathogen was characterized by bactericidal activity in the serum, phagocytic activity and reactive oxygen intermediaters (ROIs) production of olive flounder. The capsules of both bacteria, S. parauberis and S. iniae seem to be associated with the ability to resist killing activity of normal sera. Also, capsulated strains could survive in the phagocytes and induce to lower ROIs production.



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