The Preparation of Chiral Separation Membranes by UV Polymerization and its Properties

UV 중합에 의한 이성질체 분리막 제조와 특성

  • Chang, Eun-Jeong (Department of Chemical & Biochemical Engineering, Dongguk University) ;
  • Hong, Joo-Hee (Department of Chemical & Biochemical Engineering, Dongguk University) ;
  • Heo, Kwang-Beom (Department of Chemical & Biochemical Engineering, Dongguk University) ;
  • Kim, Min (Department of Safety & Environmental System Engineering, Dongguk University) ;
  • Kim, Byoung-Sik (Department of Chemical & Biochemical Engineering, Dongguk University)
  • 장은정 (동국대학교 생명.화학공학과) ;
  • 홍주희 (동국대학교 생명.화학공학과) ;
  • 허광범 (동국대학교 생명.화학공학과) ;
  • 김민 (동국대학교 안전환경시스템공학과) ;
  • 김병식 (동국대학교 생명.화학공학과)
  • Received : 2008.01.28
  • Accepted : 2008.05.09
  • Published : 2008.06.10

Abstract

Molecularly imprinted polymer (MIPs) membranes were prepared by UV polymerization to separate racemates with opposite physiological activity, and then its separation selectivity of racemates was carried out. Likewise, their properties were examined. Polycarbonate (PC) membrane was polymerized as small spot form in pore inner wall, but anodisc (AD) membrane was polymerized as film form with thickness 500~700 nm onto the membrane surface. Also the study on the separation selectivity of prepared MIPs membranes was carried out in L-Tryptophane (Trp) racemate solution. The results showed that AD MIPs membrane polymerized as a film form, which was achieved by solution polymerizaion consisting of over 90% cross-linking agent (ethylene glycol dimethacrylate; EGDMA) and under 30% dispersing agent (methanol; MeOH), had predominant 3.5 selectivity.

Acknowledgement

Supported by : 동국대학교

References

  1. D. R. Tayor and K. Maher, J. Chromatogr. Sce., 30, 67 (1992) https://doi.org/10.1093/chromsci/30.3.67
  2. S. Ahuja, Ed., Chiral Separations: Application and Technology, Am. Chem. Soc., Washington, DC (1997)
  3. J. M. Hong, P. E. Andersson, J. Qian, and C. R. Martin, Chem. Mater., 10, 1029 (1998) https://doi.org/10.1021/cm970608f
  4. H. Y. Wang, T. Kobayashi, and N. Fujii, Langmuir, 12, 4850 (1996) https://doi.org/10.1021/la960243y
  5. T. Kobayashi, H. Y. Wang, and N. Fujii, Anal. Chim. Acta., 365, 81 (1998) https://doi.org/10.1016/S0003-2670(97)00667-3
  6. M. Nakamura, S. Kiyohara, K. Saito, K. Sigita, and T. Sugo, Anal. Chem., 71, 1323 (1999) https://doi.org/10.1021/ac9805596
  7. S. Tone, T. Masawaki, and K. Eguchi, J. Membr. Sci., 118, 31 (1996) https://doi.org/10.1016/0376-7388(96)00071-3
  8. B. B. Lakshimi and C. R. Martin, Nature, 388, 758 (1997) https://doi.org/10.1038/41978
  9. A. Parthasarathy, C. J. Brumlik, C. R. Martin, and G. E. Collins, J. Membr. Sci., 94, 249 (1994) https://doi.org/10.1016/0376-7388(93)E0206-Y
  10. Y, J. Park, Technology New Brief, KISTI (2003)
  11. J. J. Ryoo, Polym. Sci. & Technol., 13, 686 (2002)
  12. H. Y. Wang, T. Kobayashi, and N. Fujii, Langmuir, 13, 5396 (1997) https://doi.org/10.1021/la970114x
  13. H. Y. Wang, G. Wulff, and A. Sahran, Angew. Chem. Int. Ed. Engl., 11, 1341 (1972)
  14. M. Yoshikawa, J. Izumi, and T. Kitao, Polym. J., 29, 205 (1997) https://doi.org/10.1295/polymj.29.205
  15. J. H, Kim, M. S. Dissertation, Chungnam National University, Daejon, Korea (2004)
  16. E. J. Chang, B. S. Kim, and M. Kim, Appli. Chem., 7, 439 (2003)
  17. L. Giorno and E, Drioli, Trends in Biotechnology, 18, 339 (2000) https://doi.org/10.1016/S0167-7799(00)01472-4
  18. M. Yoshikawa, J. Izumi, T. Kitao, and S. Sakamoto, Macromolecules, 29, 8197 (1996) https://doi.org/10.1021/ma951716v
  19. S. H. Cheong, C. Y. Oh, J. I. Seo, and J. K. Park, Korean J. Biotechnol. Bioeng., 16, 115 (2001)
  20. M. Yoshikawa, J. Izumi, and T. Kitao, Chem. Lett., 25, 611 (1996) https://doi.org/10.1246/cl.1996.611
  21. E. Marshall, Chemical and Engineering New, March 19, 38 (1990)
  22. J. Mather-Krotz and K. J. Shea, J. Am. Chem. Soc., 118, 8154 (1996) https://doi.org/10.1021/ja954066j
  23. G. Martin and P. Laffort, Oder and Deordorization in the Environ., VCH Publishers, Inc., NY, US (1994)
  24. S. Kiyohara, M. Nakamura, K. Saito, K. Sigita, and T. Sugo, J. Membr. Sci., 152, 143 (1999) https://doi.org/10.1016/S0376-7388(98)00215-4
  25. J. W Hong, UV Curing coatings, Chosun University, Gwangju, Korea (2002)
  26. E. Marshall, Science, 229, 1071 (1985)
  27. S. Tone, T. Masawaki, and T. Hamada, J. Membr. Sci., 103, 57 (1995) https://doi.org/10.1016/0376-7388(94)00307-K