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Changes in Reproductive Traits of Large White Pigs after Estrogen Receptor Gene-based Selection in Slovakia: Preliminary Results

  • Chvojkova, Zuzana (Department of Botany and Genetics, Constantine the Philosopher University) ;
  • Hraska, S. (Department of Botany and Genetics, Constantine the Philosopher University)
  • Received : 2007.05.04
  • Accepted : 2007.09.09
  • Published : 2008.03.01

Abstract

We investigated the effect of ESR gene-based selection on an improvement of litter size in the herds in real (non-experimental) conditions. The pigs were selected for three years. In the tested population the pigs were mated according to a breeding scheme where the individuals with at least one ESR-B allele were preferred in the selection. In the control group (CP; n = 140) the pigs were mated just according to a breeding scheme without knowledge of the ESR genotype. We observed a significant increase in litter size (total number of born, number of born alive and number of weaned piglets per litter) in the final tested ESR-selected population (LP; n = 184) and an insignificant increase in CP as compared with the original population (OP; n = 155). After the selection we could observe a significant increase in the frequency of allele B in LP. Frequency of the genotypes AB and BB increased in both LP and CP; the distribution of the genotypes changed significantly only in LP. An association analysis of the ESR gene effects on reproductive traits in LP showed no significant differences between the genotypes. The results of our study suggest that ESR gene-based selection can be successful also in small herds, under real (non-experimental) conditions with a respect for general breeding principles and limitations and during a short period. An examination of a larger sample population as well as an analysis of selection consequences on other traits (meat and carcass quality) could bring a more conclusive evaluation of ESR-based selection. Nevertheless, the results are encouraging especially for small breeding farms taking a perspective of better litter size improvement.

Keywords

ESR Gene;Litter Size;Pigs;Selection

Acknowledgement

Supported by : Ministry of Education, Slovakia

References

  1. Omelka, R., D. Peskovicova, M. Martiniakova, M. Bauer and M. Bauerova. 2006. Effect of the estrogen receptor (ESR) and ryanodine receptor (RYR1) genes on reproductive traits of Slovak Large White, White Meaty and Landrace pigs. Arch. Tierz. 49:357-362.
  2. Omelka, R., M. Bauerova, J. Mlynek, B. Buchova, D. Peskovicova. and J. Bulla. 2005a. Effects of the oestrogen receptor (ESR) gene on reproductive traits of Large White, White Meaty and Landrace pigs. Czech J. Anim. Sci. 50:249-253.
  3. Omelka, R., D. Peskovicova, M. Martiniakova and M. Bauerova. 2005b. Effect of Ava I and MspA1 I polymorphisms in the estrogen receptor gene (ESR) on litter size in Large White and Landrace pigs. J. Farm Anim. Sci. 38:35-40.
  4. Omelka, R., D. Vasicek, M. Martiniakova, J. Bulla and M. Bauerova. 2004. Simultaneous detection of malignant hyperthermia and genetic predisposition for improved litter size in pigs by multiplex PCR-RFLP. Folia biologica (Krakow). 52:113-115.
  5. Matousek, V., N. Kernerova, O. Kolarikova, H. Krizova, T. Urban and I. Vrtkova. 2003. Effect of RYR1 and ESR genotypes on the fertility of sows of Large White breed in elite herds. Czech J. Anim. Sci. 48:129-133
  6. Nguyen, N. H. and C. P. McPhee. 2005. Genetic parameters and responses of performance and body composition traits in pigs selected for high and low growth rate on a fixed ration over a set time. Genet. Sel. Evol. 37:199-213. https://doi.org/10.1186/1297-9686-37-3-199
  7. Niu, B. Y., Y. Z. Xiong, S. W. Jiang, F. E. Li, C. Y. Deng, S. H. Ding, W. H. Guo, M. G. Lei, R. Zheng, B. Zuo, D. Q. Xu and J. L. Li. 2006. Oviduct-specific glycoprotein 1 locus is associated with litter size and weight of ovaries in pigs. Asian-Aust. J. Anim. Sci. 19:632-637. https://doi.org/10.5713/ajas.2006.632
  8. Noguera, J. L., L. Varona, L. Gomez-Raya, A. Sanchez, D. Babot, J. Estany, L. A. Messer, M. Rothschild and M. Perez-Enciso. 2003. Liv. Prod. Sci. 82:53-59. https://doi.org/10.1016/S0301-6226(03)00004-6
  9. Kmiec, M., J. Dvorak and I. Vrtkova. 2002. Study on a relation between estrogen receptor (ESR) gene polymorphism and some pig reproduction performance characters in Polish Landrace breed. Czech J. Anim. Sci. 47:189-193.
  10. Lukovic, Z., M. Uremovic, M. Konjacic, Z. Uremovic and D. Vincek. 2007. Genetic parameters for litter size in pigs using a random regression model. Asian-Aust. J. Anim. Sci. 20:160- 165.
  11. Omelka, R., M. Bauerova and J. Bulla. 2001. Genetic markers for reproductive traits in pigs. Agric. 10:731-740.
  12. Short, T. H., M. F. Rothschild, O. I. Southwood, D. G. McLaren, A. de Vries, H. van der Steen, G. R. Eckardt, C. K. Tuggle, J. Helm, D. A. Vaske, A. J. Mileham and G. S. Plastow. 1997. Effect of estrogen receptor locus on reproduction and production traits in four commercial pig lines. J. Anim. Sci. 75: 3138-3142. https://doi.org/10.2527/1997.75123138x
  13. Vrtkova, I. and J. Dvorak. 2001. Genetic variability in the ESR locus in pigs of the Landrace and Large White breeds kept in the Czech republic. Czech J. Anim. Sci. 46:185-187.
  14. Rothschild, M. F., Z. H. Hu and Z. Jiang. 2007. Advances in QTL mapping in pigs. Int. J. Biol. Sci. 10:192-197.
  15. SAS v 8.2: SAS Institute Inc., Cary, USA, 2002.
  16. Schwab, C. R., T. J. Baas, K. J. Stalder and J. W. Mabry. 2006. Effect of long-term selection for increased leanness on meat and eating quality traits in Duroc swine. J. Anim. Sci. 84: 1577-1583. https://doi.org/10.2527/2006.8461577x
  17. Peskovicova, D., J. Wolf, E. Groeneveld and M. Wolfova. 2002. Simultaneous estimation of the covariance structure of traits from field test, station test and litter recording in pigs. Liv. Prod. Sci. 77:155-165. https://doi.org/10.1016/S0301-6226(02)00064-7
  18. Rothschild, M. F., C. Jacobson, D. A. Vaske, C. K. Tuggle, L. Wang, T. Short, G. Eckardt, S. Sasaki, A. Vincent, D. G. McLaren, O. Southwood, H. van der Steen, A. Mileham and G. S. Plastow. 1996. The estrogen receptor locus is associated with a major gene influencing litter size in pigs. Proc. Natl. Acad. Sci. 93:201-205. https://doi.org/10.1073/pnas.93.1.201
  19. Goliasova, E. and J. Wolf. 2004. Impact of the ESR gene on litter size and production traits in Czech Large White pigs. Anim. Genet. 35:293-297. https://doi.org/10.1111/j.1365-2052.2004.01155.x
  20. Kaminski, S., A. Rusc and P. Brym. 2003. Relation between Ava I polymorphism within the estrogen receptor gene (ESR) and meatiness in Polish Large White boars. J. Appl. Genet. 44:521-524.
  21. Alfonzo, L. 2005. Use of meta-analysis to combine candidate gene association studies: application to study the relationship between the ESR PvuII polymorphism and sow litter size. Genet. Sel. Evol. 37:417-435. https://doi.org/10.1186/1297-9686-37-5-417
  22. Bidanel, J. P., J. Gruand and C. Legault. 1994. An overview of twenty years of selection for litter size in pigs using 'hyperprolific' schemes. Proc. 5th World Cong. on Genet. Appl. Livest. Prod. 17:512-515.
  23. Buske, B., I. Sternstein and G. Brockmann. 2006. QTL and candidate genes for fecundity in sows. Anim. Reprod. Sci. 95: 167-183. https://doi.org/10.1016/j.anireprosci.2005.12.015
  24. Cameron, N. D. and M. K. Curran. 1995. Responses in carcass composition to divergent selection for components of efficient lean growth rate in pigs. Anim. Sci. 61:347-359. https://doi.org/10.1017/S1357729800013904
  25. Li, K., M. J. Zhu, M. Yu, B. Liu, Z. Z. Zhu, T. A. Xiong, B. Fan, S. P. Xu, Y. Q. Du, Z. Z. Peng and K. Li. 2004. Genetic status of ESR locus and other unidentified genes associated with litter size in Chinese indigenous Tongcheng pig breed after a long time selection. Asian-Aust. J. Anim. Sci. 17:598-602. https://doi.org/10.5713/ajas.2004.598