Process analytical technology (PAT): new paradigm for the state-of-the-art analytical technology

공정분석기술: 첨단 분석기술의 새로운 패러다임

  • Kim, Jong-Yun (Korea Atomic Energy Research Intitute) ;
  • Park, Yong Joon (Korea Atomic Energy Research Intitute) ;
  • Yeon, Jei-Won (Korea Atomic Energy Research Intitute) ;
  • Woo, Young-Ah (Korea United Pharm. Inc.) ;
  • Kim, Hyo-Jin (Department of Pharmacy, Dongduk Women's) ;
  • Song, Kyuseok (Korea Atomic Energy Research Intitute)
  • 김종윤 (한국원자력연구원 원자력화학연구부) ;
  • 박용준 (한국원자력연구원 원자력화학연구부) ;
  • 연제원 (한국원자력연구원 원자력화학연구부) ;
  • 우영아 ((주) 한국유나이티드제약 제제연구소) ;
  • 김효진 (동덕여자대학교 약학과) ;
  • 송규석 (한국원자력연구원 원자력화학연구부)
  • Received : 2008.08.19
  • Accepted : 2008.10.06
  • Published : 2008.10.25


Process analytics has been already widely utilized in a large-scale continuous production line such as petroleum industries for several decades. Although the process analytics has a long history, a concept of "Process Analytical Technology (PAT)" has been rapidly adopted as a new paradigm for the process monitoring in the production process of various industries. In this review, current status and recent developments of PAT in various research bodies have been introduced, including the introduction of various types of analytical instruments, chemometrics tools, and perspectives and future applications of PAT as well as the fundamentals on PAT such as terminology and its historical background.


Process analytical technology;process analytical chemistry;chemometrics;design of experiment;process monitoring;process analytics


Supported by : 과학기술부


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