Effects of Chromium Picolinate Supplementation on Growth Hormone Secretion and Pituitary mRNA Expression in Finishing Pigs

DOI QR코드

DOI QR Code

Wang, M.Q.;He, Y.D.;Xu, Z.R.;Li, W.F.

  • 투고 : 2007.11.26
  • 심사 : 2008.03.17
  • 발행 : 2008.07.01

초록

The purpose of the present study was to investigate the effects of chromium picolinate (CrPic) on growth hormone (GH) secretion and pituitary GH mRNA expression in finishing pigs. Forty eight crossbred pigs with an initial body weight of 65.57 kg (SD = 1.05) were blocked by body weight and randomly assigned to two treatments with three replicates. Each group was fed the diet supplemented with or without $200{\mu}g/kg$ chromium from CrPic for 40 days. The results showed that average daily gain of pigs was increased by 9.84% (p<0.05), and longissimus muscle area was increased by 17.29% (p<0.05) with the supplementation of CrPic. The results of GH dynamic secretion showed that supplemental CrPic increased the mean level and peak value of GH by 36.58% (p<0.05) and 26.60% (p<0.05), respectively, while there was no significant effect on basal value, peak amplitude and peak duration. Pituitary mRNA expression of GH was not significantly influenced by supplemental CrPic. These results indicated that CrPic increased pigs GH secretion without change of pituitary GH mRNA expression.

키워드

Chromium Picolinate;Pigs;Growth Hormone

참고문헌

  1. Boleman, S. L., S. J. Boleman, T. D. Bidner, L. L. Southern, T. L. Ward, J. E. Pontif and M. M. Pike. 1995. Effect of chromium picolinate on growth, body composition, and tissue accretion in pigs. J. Anim. Sci. 73:2033-2042. https://doi.org/10.2527/1995.7372033x
  2. Bunting, L. D., J. M. Fernandez, D. L. Jr. Thompson and L. L. Southern. 1994. Influence of chromium picolinate on glucose usage and metabolic criteria in growing Holstein calves. J. Anim. Sci. 72:1591-1599. https://doi.org/10.2527/1994.7261591x
  3. Evock-Clover, C. M., M. M. Polansky, R. A. Anderson and N. C. Steele. 1993. Dietary chromium supplementation with or without somatotropin treatment alters serum hormones and metabolites in growing pigs without affecting growth performance. J. Nutr. 123:1504-1512. https://doi.org/10.1093/jn/123.9.1504
  4. Guan, X., J. J. Matte, P. R. Ku, J. L. Snow, J. L. Burton and N. L. Trottier. 2000. High chromium yeast supplementation improves glucose tolerance in pigs by decreasing hepatic extraction of insulin. J. Nutr. 130:1274-1279. https://doi.org/10.1093/jn/130.5.1274
  5. Anderson, R. A. 1987. Chromium. In: Trace elements in human and animal nutrition (5th Ed.) (Ed. W. Mertz). p. 225. Academic Press, San Diego, CA.
  6. AOAC. 1995. Official Methods of Analysis. 16th ed. Assoc. Off. Anal. Chem. Arlington, VA.
  7. Barb, C. R., R. R. Kraeling and G. B. Rampacek. 2002. Metabolic regulation of the neuroendocrine axis in pigs. Reprod. Suppl. 59:203-217.
  8. Mooney, K. W. and G. L. Cromwell. 1995. Effects of dietary chromium picolinate supplementation on growth, carcass characteristics, and accretion rates of carcass tissues in growing-finishing swine. J. Anim. Sci. 73:3351-3357. https://doi.org/10.2527/1995.73113351x
  9. Mooney, K. W. and G. L. Cromwell. 1996. Effects of chromium picolinate on growth performance and tissue accretion in pigs with different lean gain potential. J. Anim. Sci. 74 (Suppl.): 65 (Abstr.).
  10. Mooney, K. W. and G. L. Cromwell. 1997. Efficacy of chromium picolinate and chromium chloride as potential modifiers in swine. J. Anim. Sci. 75:2661-2671. https://doi.org/10.2527/1997.75102661x
  11. National Research Council (NRC). 1997. The role of chromium in animal nutrition. National Academy Press, Washington, DC. p. 80.
  12. National Research Council (NRC). 1998. Nutrient Requirements of Swine, 10th edn. National Academy Press, Washington, DC.
  13. Okada, S., M. Susuki and H. Ohba. 1983. Enhancement of ribonucleic acid synthesis by chromium (III) in mouse liver. J. Inorg. Biochem. 19:95-103. https://doi.org/10.1016/0162-0134(83)85015-6
  14. Lien, T. F., K. H. Yang and K. J. Lin. 2005. Effects of chromium propionate supplementation on growth performance, serum traits and immune in weaned pigs. Asian-Aust. J. Anim. Sci. 18:403-409. https://doi.org/10.5713/ajas.2005.403
  15. Lindemann, M. D., C. M. Wood, A. F. Harper, E. T. Kornegay and R. A. Anderson. 1995. Dietary chromium picolinate additions improve gain:feed and carcass characteristics in growingfinishing pigs and increase litter size in reproducing sows. J. Anim. Sci. 73:457-465. https://doi.org/10.2527/1995.732457x
  16. Matthews, J. O., A. D. Higbie, L. L. Southern, D. F. Coombs, T. D. Bidner and R. L. Odgaard. 2003. Effect of chromium propionate and metabolizable energy on growth, carcass traits, andpork quality of growing-finishing pigs. J. Anim. Sci. 81:191-196. https://doi.org/10.2527/2003.811191x
  17. Xi, G., Z. R. Xu, S. H. Wu and S. J. Chen. 2001. Effect of chromium picolinate on growth performance, carcass characteristics, serum metabolites and metabolism of lipid in pigs. Asian-Aust. J. Anim. Sci. 14:258-264. https://doi.org/10.5713/ajas.2001.258
  18. Ward, T. L., L. L. Southern and R. A. Anderson. 1995. Effect of dietary chromium source on growth, carcass characteristics, and plasma metabolite and hormone concentrations in growing-finishing swine. J. Anim. Sci. 73(Suppl.):189(Abstr.).
  19. Steele, N. C., T. G. Althen and L. T. Frobish. 1977. Biological activity of glucose tolerance factoring swine. J. Anim. Sci. 45:1341-1345. https://doi.org/10.2527/jas1977.4561341x
  20. Wang, M. Q. and Z. R. Xu. 2004. Effect of chromium nanoparticle on growth performance, carcass characteristics, pork quality and tissue chromium in finishing pigs. Asian-Aust. J. Anim. Sci. 17:1118-1122. https://doi.org/10.5713/ajas.2004.1118
  21. Wang, M. Q., Z. R. Xu, L.Y. Zha and M. D. Lindemann. 2007. Effects of chromium nanocomposite supplementation on blood metabolites, endocrine parameters and immune traits in finishing pigs. Anim. Feed Sci. Technol. 139:69-80. https://doi.org/10.1016/j.anifeedsci.2006.12.004
  22. SAS (Statistical Analysis System Inc.). 1989. SAS/STAT User's Guide. Version 6. SAS Institute Inc., Cary, NC.
  23. Schram, E., S. Moore and E. W. Bigwood. 1954. Chromatographic determination of cystine as cystic acid. Biochem. J. 57:33-37. https://doi.org/10.1042/bj0570033
  24. Shelton, J. L., R. L. Payne, S. L. Johnston, T. D. Bidner, L. L. Southern, R. L. Odgaard and T. G. Page. 2003. Effect of chromium propionate on growth, carcass traits, pork quality, and plasma metabolites in growing-finishing pigs. J. Anim. Sci. 81:2515-2524. https://doi.org/10.2527/2003.81102515x
  25. Okada, S., M. Taniyama and H. Ohba. 1982. Mode of enhancement in ribonucleic acid synthesis directed by chromium (III)-bound deoxyribonucleic acid. J. Inorg. Biochem. 17:41-49. https://doi.org/10.1016/S0162-0134(00)80228-7
  26. Okada, S., H. Tsukada and H. Ohba. 1984. Enhancement of nuclear RNA synthesis by chromium (III) in regenerating rat liver. J. Inorg. Biochem. 21:113-124. https://doi.org/10.1016/0162-0134(84)85044-8
  27. Okada, S., H. Tsukada and M. Tezuka. 1989. Effect of chromium (III) on nucleolar RNA synthesis. Biol. Trace Elem. Res. 21:35-39. https://doi.org/10.1007/BF02917234
  28. Page, T. G., L. L. Southern, T. L. Ward and D. L. Jr. Thompson. 1993. Effect of chromium picolinate on growth and serum and carcass traits of growing-finishing pigs. J. Anim. Sci. 71:656-662. https://doi.org/10.2527/1993.713656x
  29. Roginski, E. E. and W. Mertz. 1969. Effects of chromium (III) supplementation on glucose and amino acid metabolism in rats fed a low protein diet. J. Nutr. 97:525-530. https://doi.org/10.1093/jn/97.4.525
  30. Merriam, G. R. and K. W. Wachter. 1982. Algorithms for the study of episodic hormone secretion. Am. J. Physiol. Endocrinol. Metab. 243:E310-E318. https://doi.org/10.1152/ajpendo.1982.243.4.E310

과제정보

연구 과제 주관 기관 : National Natural Science Foundation of China