2종의 경화액과 혼합된 calcium phosphate cement의 유변학적 성질에 관한 연구

Rheological Properties of Calcium Phosphate Cement Mixed with 2 Kinds of Setting Solution

  • 장석우 (성균관대학교 의과대학 삼성서울병원 치과진료부 보존과) ;
  • 권호범 (성균관대학교 의과대학 삼성서울병원 치과진료부 보철과) ;
  • 유현미 (성균관대학교 의과대학 삼성서울병원 치과진료부 보존과) ;
  • 박동성 (성균관대학교 의과대학 삼성서울병원 치과진료부 보존과) ;
  • 오태석 (성균관대학교 의과대학 삼성서울병원 치과진료부 보존과) ;
  • 배광식 (서울대학교 치의학전문대학원 보존학 교실)
  • Chang, Seok-Woo (Department of Conservative Dentistry, The institute of Oral Health Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kwon, Ho-Beom (Department of Prosthodontics, The institute of Oral Health Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Yoo, Hyun-Mi (Department of Conservative Dentistry, The institute of Oral Health Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Park, Dong-Sung (Department of Conservative Dentistry, The institute of Oral Health Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Oh, Tae-Seok (Department of Conservative Dentistry, The institute of Oral Health Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Bae, Kwang-Shik (Department of Conservative Dentistry, School of Dentistry, Seoul National University)
  • 투고 : 2008.05.15
  • 심사 : 2008.09.25
  • 발행 : 2008.09.30

초록

Calcium phosphate cement (CPC)는 우수한 생체 친화성을 바탕으로 치과 및 의과 쪽에서 성공적인 bone substitute로 사용되어 왔다. 긴 경화시간 및 washout tendency 등 CPC의 단점을 개선하기 위해 다양한 종류의 경화액 및 첨가제등에 대한 연구가 이루어졌다. 그러나 첨가제의 종류에 따른 CPC paste의 점탄성을 정량적으로 비교한 연구는 많지 않다. 이 연구에서는 2% hydroxyprophyl methylcellulose (HPMC)와 35% polyacrylic acid (PAA)의 두 가지 경화액과 혼합된 CPC의 유변학적 성질을 관찰하고 비교하고자 하였다. Dicalcium phosphate dihydrate (DCPD)를 2% HPMC 및 35% PAA와 각각 1:1의 분액비로 30초간 섞은 후 cone and plate geometry를 가지는 rheometer를 사용하여 frequency sweep test와 time sweep test를 통해 shear storage modulus (G'), shear loss modulus (G''), 그리고 complex viscosity (${\eta}^*$)를 측정하였다. 2% HPMC군과 35% PAA군의 complex viscostiy의 차이를 Mann-whitney test with Bonferroni's collection을 사용하여 분석하였다. 실험결과 2% HPMC 및 35% PAA 군 모두에서 shear thinning과 yield behavior등 pseudoplastic property를 보였으며 complex viscosity는 HPMC 군에서 PAA 군보다 통계적으로 유의성 있게 높았다. (p<0.05).

키워드

칼슘인산계시멘트;하이드록시프로필 메틸셀룰로오스;폴리아크릴산;유변학적 성질

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