Comparative studies of histopathologic pulmonary lesion of cattle and deer tuberculosis by Mycobacterium bovis

Mycobacterium bovis에 의한 소 및 사슴 결핵의 폐 병리조직학적 소견 비교연구

  • Jean, Young Hwa (National Veterinary Research and Quarantine Service) ;
  • Roh, In Soon (National Veterinary Research and Quarantine Service) ;
  • Lee, Kyung Hyun (National Veterinary Research and Quarantine Service) ;
  • Lee, Kyung Woo (National Veterinary Research and Quarantine Service) ;
  • Cho, Yoon Sang (National Veterinary Research and Quarantine Service) ;
  • Joo, Yi Seok (National Veterinary Research and Quarantine Service)
  • Accepted : 2008.05.29
  • Published : 2008.08.01

Abstract

Comparative studies of histopathologic lesions from 23 purified protein derivative (PPD) positive cattle, 21 slaughter cattle found with tuberculosis, and 11 tuberculosis-positive elk (Cervus elaphus) were performed. PPD positive cattle did not show specific histopathologic lesions in all 23 heads that were no visible lesion reactor. Slaughter cattle found with tuberculosis revealed microscopically classical granulomatous lesion (tubercle) with central caseous necrosis surrounded by mantle of epithelioid cells and Langhan's giant cells capsuled by connective tissue in lung. Elk was noted with some different lesion patterns with classical granulomatous lesion and suppurative abscesses that was composed of fibrin, degenerated cells without having connective tissue. In addition, many Langhan's giant cells infiltration in alveoli at peripheral lesion were observed in some cases of classical granulomatous lesion and suppurative abscesses.

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