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Screening of Biological Activities of Extracts from Rhododendron mucronulatum Turcz. Flowers

진달래꽃(Rhododendron mucronulatum Turcz. Flower) 추출물의 생리활성 탐색

  • 조영제 (경북대학교 식품공학과) ;
  • 주인식 (경북대학교 식품공학과) ;
  • 천성숙 (영남대학교 식품가공학과) ;
  • 안봉전 (대구한의대학교 화장품약리학과) ;
  • 김정환 (엔아이피 바이오텍) ;
  • 김명욱 (경북해양바이오 산업연구원) ;
  • 권오준 (경북전략산업기획단)
  • Published : 2008.03.31

Abstract

Extracts from Rododendron mucronulatum Turcz. flowers were tested for antioxidant and their inhibitory activities of ${\alpha}$-amylase, ${\alpha}$-glucosidase and angiotensin converting enzyme (ACE). Total contents of phenolics were found as $30.6{\pm}0.14mg/g$ (60% EtOH extract) and $23.2{\pm}0.21mg/g$ (water extract). Electron donation ability (EDA), ABTS [2,2azinobis(3-ethylbenzothiazoline-6-sulfonic acid)] radical decolorization, Antioxidant protection factor (PF) and thiobarbituric acid reactive substance (TBARs) were measured for the antioxidative activity of the extracts from Rododendron mucronulatum Turcz. flowers. The water extract were determined as 97.5% at ethanol extract showed 83.2% and 60% EtOH extract were 89.7% in EDA. The water extract showed higher antioxidant activity than 60% EtOH extract when evaluated by ABTS radical decolorization and antioxidant PF. The TBARS of water extracts and 60% EtOH extracts were shown as $0.29{\times}10^2{\mu}M\;and\;0.28{\times}10^2{\mu}M$, respectively, and were lower than control. ACE inhibitory activity in water extract (67.6% inhibition) was higher than that of 60% EtOH extract (46.7% inhibition) at $200{\mu}g/mL$. Water extracts had higher inhibitory activities on ${\alpha}$-amylase and ${\alpha}$-glucosidase than 60% EtOH extracts. The result suggests that the water extract from Rododendron mucronulatum Turcz. flowers will be useful as natural antioxidants and functional foods.

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