Development of a Characteristic Point Detection Algorithm for the Calculation of Pulse Wave Velocity

맥파전달속도 계산을 위한 특징점 검출 알고리즘 개발

  • 이낙범 (전주비전대학 의료기정보과) ;
  • 임재중 (전북대학교 전자정보공학부)
  • Published : 2008.05.01

Abstract

Shape of the pulse waveform is affected by the visco-elasticity characteristics of the arterial wall and the reflection waves generated at the bifurcations of arterial branches. This study was designed to improve the accuracy for the extraction of pulse wave features, then proved the superiority of the developed algorithm by clinical evaluation. Upstroke point of the pulse wave was used as an extraction feature since it is minimally affected by the waveform variation. R-peak of the ECG was used as a reference to decide the minimum level, then intersection of the least squares of regression line was used as an upstroke point. Developed algorithm was compared with the existing minimum value detection algorithm and tangent-intersection algorithm using data obtained from 102 subjects. Developed algorithm showed the least standard deviation of $0.29{\sim}0.44\;m/s$ compared with that of the existing algorithms, $0.91{\sim}3.66\;m/s$. Moreover, the rate of standard deviation of more than 1.00m/s for the PWV values reduced with the range of $29.0{\sim}42.4%$, which proved the superiority of the newly developed algorithm.

Keywords

PWV;Pulse wave velocity;Intersecting tangent method;Least square method

References

  1. W. Schimmler, "Correlations between the pulse wave velocity in the aortic illiac vessel, and age, sex, and blood pressure", Angiology, Vol. 17, pp. 314-322, 1966 https://doi.org/10.1177/000331976601700508
  2. F. Hansen, P. Mangell, B. Sonesson and T. Lanne, "Diameter and compliance in the human common carotid artery - variation with age and sex", Ultrasound in Med. & Biol., Vol. 21, No. 1, pp. 1-9, 1995
  3. B.M. Pannier, M.E. safar, S. Laurent and G.M. London, "Indirect, noninvasive evaluation of pressure wave transmission in essential hypertension", Angiology, Vol. 40, pp. 29-35, 1989 https://doi.org/10.1177/000331978904000106
  4. R. Asmar, "Arterial stiffness and pulse wave velocity clinical applications", Elsevier, 1999
  5. R.H. Turner and G.R. Herrmann, "Pulse wave velocity undervarying conditions in normal and abnormal human cardiovascular system", J. Clin. Invest., Vol. 4, p. 430, 1927
  6. B. Stanley, "Abrams' angiography", Little, Brown and Company, 1997
  7. R.P. Kelly, C. Hayward, A.P. Avolio and M.F. O'Rourke, "Noninvasive determination of age-related changes in the human arterial pulse", Circulation, Vol. 80, pp. 1652-1659, 1989 https://doi.org/10.1161/01.CIR.80.6.1652
  8. J. Longhurst, RJ. Capone, DT. Mason, R. Zelis, "Comparison of blood flow measured by plethysmograph and flowmeter during steady state forearm exercise", Circulation, Vol. 49, pp.535-540, 1974 https://doi.org/10.1161/01.CIR.49.3.535
  9. E.D. Lehmann, K.D. Hopkins, A. Rawesh, R.C. Joseph, K. Kongola, S.W. Coppack and R.G. Gosling, "Relation between number of cardiovascular risk factors/events and noninvasive doppler ultrasound assessments of aortic compliance", Hypertension, Vol. 32, pp. 565-569, 1998 https://doi.org/10.1161/01.HYP.32.3.565
  10. Y.C. Chiu, P.W. Arand, S.G. Shroff, T. Feldman and J.D. Carroll, "Determination of pusle wave velocities with computerized algorithms", Am. Heart J., Vol121, No. 5, pp. 1460-1470, 1991 https://doi.org/10.1016/0002-8703(91)90153-9
  11. E.D. Lehmann, R.G. Gosling, B. Fatemi-Langroudi and M.G. Taylor, "Non-invasive Doppler ultrasound technique for the in vivo assessment of aortic compliance", J. Biomed. Eng., Vol. 14, pp. 250-256, 1992 https://doi.org/10.1016/0141-5425(92)90060-X
  12. M. Okada, T. Matsuto, O. Sugita, T. Yamada, "Use of heart rate variability and pulse wave volocity for diagnosing cardiovascular autonomic neuropathy", Rinsho Byori, Vol.40, pp. 655-659, 1992
  13. M.F. O'Rourke, R.P. Kelly, "Wave reflection in the systemic circulation and its implications in ventricular function", J. Hypertens., Vol. 11, pp. 327-337, 1993 https://doi.org/10.1097/00004872-199304000-00001