Increment of Physiologically Active Compounds in Germinated Brown Rice Treated with Chitosan and its Effect on Obesity of Rat Fed a High Fat Diet

키토산을 처리한 발아현미의 기능성분 증대 및 비만에 미치는 영향

  • Li, Hua (Dept. of Food Engineering and Solar Salt Biotechnology Research Center, Mokpo National University) ;
  • Cho, Jeong-Yong (Dept. of Food Engineering and Solar Salt Biotechnology Research Center, Mokpo National University) ;
  • Gao, Tian-Cheng (Dept. of Food Engineering and Solar Salt Biotechnology Research Center, Mokpo National University) ;
  • Choi, Cha-Ran (Dept. of Food Engineering and Solar Salt Biotechnology Research Center, Mokpo National University) ;
  • Lee, Kang-Deok (Dept. of Food Engineering and Solar Salt Biotechnology Research Center, Mokpo National University) ;
  • Cho, Ji-Eun (Biotech. Co. Ltd.) ;
  • Cho, Geon-Sik (Biotech. Co. Ltd.) ;
  • Ham, Kyung-Sik (Dept. of Food Engineering and Solar Salt Biotechnology Research Center, Mokpo National University)
  • 이화 (목포대학교 식품공학과 및 천일염생명과학연구소) ;
  • 조정용 (목포대학교 식품공학과 및 천일염생명과학연구소) ;
  • 고천성 (목포대학교 식품공학과 및 천일염생명과학연구소) ;
  • 최차란 (목포대학교 식품공학과 및 천일염생명과학연구소) ;
  • 이강덕 (목포대학교 식품공학과 및 천일염생명과학연구소) ;
  • 조지은 (바이오테크(주)) ;
  • 조건식 (바이오테크(주)) ;
  • 함경식 (목포대학교 식품공학과 및 천일염생명과학연구소)
  • Published : 2008.08.30


This study was to investigated the changes of physiologically active components in germinated brown rice treated with chitosan (CGBR) and its anti-obesity effect in rat fed a high fat diet. Contents of physiologically active compounds such as total phenolic compounds, total dietary fiber, $\gamma$-aminobutyric acid (GABA), and total phytic acid in CGBR were significantly higher than those of traditional germinated brown rice (GBR). Lipase inhibitory activity of CGBR was higher than those of GBR and brown rice (BR). High fat diets containing CGBR, GBR, and BR were administered to three groups of male Sprague-Dawley rats for four weeks. All groups showed no significant difference in body weight, total abdominal fat, and plasma lipid levels. However, CGBR group appeared to have lower body weight gain and total abdominal fat level than other groups fed high fat diets containing GBR and BR. Total cholesterol and LDL-cholesterol contents in plasma of CGBR group were also lower than those of other groups. Thus, new germination method of brown rice using chitosan is a useful process, which utilizes plant defense responses to elevate the production of secondary metabolites and anti-obesity effect.


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