Inhibitory Effects of an Eicosanoid Biosynthesis Inhibitor, Benzylideneacetone, Against Two Spotted Spider Mite, Tetranychus urticae, and a Bacterial Wilt-causing Pathogen, Ralstonia solanacearum

아이코사노이드 생합성 저해제인 벤질리덴아세톤의 점박이응애(Tetranychus urticae)와 세균성풋마름병 세균(Ralstonia solanacearum)에 대한 억제효과

  • Park, Ye-Sol (School of Bioresource Sciences, Andong National Sciences) ;
  • Kim, Min-Je (School of Bioresource Sciences, Andong National Sciences) ;
  • Lee, Geon-Hyung (Agrcultural Environmental Research Center, NABIS Co., Ltd.) ;
  • Chun, Won-Soo (School of Bioresource Sciences, Andong National Sciences) ;
  • Yi, Young-Keun (School of Bioresource Sciences, Andong National Sciences) ;
  • Kim, Yong-Gyun (School of Bioresource Sciences, Andong National Sciences)
  • 박예슬 (안동대학교 생명자원과학부) ;
  • 김민제 (안동대학교 생명자원과학부) ;
  • 이건형 ((주)나비스) ;
  • 천원수 (안동대학교 생명자원과학부) ;
  • 이영근 (안동대학교 생명자원과학부) ;
  • 김용균 (안동대학교 생명자원과학부)
  • Published : 2009.09.30

Abstract

A monoterpenoid compound, benzylideneacetone (BZA), is a metabolite of an entomopathogenic bacterium, Xenorhabdus nematophila. Its primary biological activity is an inhibitor of phospholipase $A_2$, which catalyzes the committed step of biosynthesis of various eicosanoids that are critically important to mediate insect immune responses. When BZA was applied to two-spotted spider mite, Tetranychus urticae, it exhibited a dose-dependent mortality in leaf-disc assay. Subsequently BZA was tested against T. urticae infesting apples in a field orchard, in which it showed a significant control efficacy, which was not statistically different with that of a commercial acaricide. BZA also had significant antibacterial activities against three species of plant pathogenic bacteria when it was added to the bacterial cultures, in which it showed the highest inhibitory activity against a bacterial wilt-causing pathogen, Ralstonia solanacearum. The bacterial pathogen caused significant disease symptom to young potato plants. However, BZA significantly suppressed the disease occurrence. This study suggests that BZA can be used to develop a novel crop protectant to control mite and bacterial pathogen.

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