Growth Rate study of CPAE Cells and Osteobalst by Local Hyperthermia Duplex Stainless Steel Thermo-rod

국소온열치료용 듀플렉스 스테인리스 스틸 발열체에 의한 혈관세포와 골세포의 온도에 따른 성장률 변화 관찰

  • 최성민 (부산가톨릭대학교 치기공학과) ;
  • 김영곤 (인제대학교 의용공학과)
  • Published : 2009.11.28


We investigated the cell growth rate according to the change of temperature of the Thermo-rod used for the local hyperthermia therapy. For this study, we fabricated the Thermo-rods (TR) using Duplex Stainless Steels having magnetic properties as well as non magnetic properties. To evaluate cell growth rates up to 15 days, we conducted cell proliferation test using cell counting methods. For the tests, the CAPEs and Osteoblats were seeded on the 6-we11 plates with the induction heated thermo-rods 30 mins a day for 15 days with 2 days interval and without induction heated thermo-rods as control group respectively. We calculated cell growth rates, 6 hours after heating. From the results, in case of CAPEs and Osteobalsts seeded groups, the cell growth rates in all groups increased drastically for 6 days after seeding, but decreased irregularly after 6 days. In conclusion, the cell growth rates showed no significant difference among all groups and it indicated that there were no effects of temperate ($41^{\circ}C$) on cell growth rates.


Local Hyperthermia;Duplex Stainless Steel;Cell Growth Rate


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