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A pilot clinical study on the Traditional Korean Medicine treatment of Amyotrophic lateral sclerosis

근위축성 측삭경화증에 대한 한방 치료의 임상선행연구

  • Kim, Sung-Chul (Dept. of Acupuncture & Moxibustion, Gwang-Ju Oriental Medical Hospital, Wonkwang University) ;
  • Na, Won-Min (Dept. of Acupuncture & Moxibustion, Gwang-Ju Oriental Medical Hospital, Wonkwang University) ;
  • Lim, Na-Ra (Dept. of Acupuncture & Moxibustion, Gwang-Ju Oriental Medical Hospital, Wonkwang University) ;
  • Lee, Do-Sang (Dept. of Acupuncture & Moxibustion, Gwang-Ju Oriental Medical Hospital, Wonkwang University) ;
  • Jang, Eun-Ha (Dept. of Acupuncture & Moxibustion, Gwang-Ju Oriental Medical Hospital, Wonkwang University) ;
  • Song, Bong-Keun (Dept. of Internal Medicine, Gwang-Ju Oriental Medical Hospital, Wonkwang University)
  • 김성철 (원광대학교 광주 한방병원 침구과) ;
  • 나원민 (원광대학교 광주 한방병원 침구과) ;
  • 임나라 (원광대학교 광주 한방병원 침구과) ;
  • 이도상 (원광대학교 광주 한방병원 침구과) ;
  • 장은하 (원광대학교 광주 한방병원 침구과) ;
  • 송봉근 (원광대학교 광주 한방병원 6내과)
  • Published : 2009.03.30

Abstract

Objectives : This study was to investigate the effect of Oriental medical treatment on ALS. Methods : We investigated 12 ALS patients which were admitted to Gwang-Ju O.M. hospital from Oct. 14, 2008 to Nov. 14, 2008. All patients were treated by SAAM-acupuncture, herb medication, Bee venom Pharmacopuncture therapy, Needle-embedding therapy, etc. We evaluated patients using the Amyotrophic lateral sclerosis Functional Rating Scale-Revised(ALSFRS-R), Medical Research Council (MRC) Scale. Results : After 30 days, mean ALSFRS-R score of patients was improved from $28.42{\pm}7.83$ to $29.08{\pm}7.99$, and mean MRC Scale of patients was improved from $24.79{\pm}8.37$ to $25.34{\pm}8.45$. But in both cases, the variation was not statistically significant. After 30 days, mean ALSFRS-R score and mean MRC Scale of patients was more improved in subjects with bulbar-onset, onset age: 51-60yrs., disease duration: 24-48mo. And the results showed partially significant difference. Conclusions : We think that the results of this case be a pilot study that proves the effect of Oriental Medical treatment on ALS.

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