Distribution of hazardous heavy metals in commercial herbal medicines classified by plant parts used in seoul

서울지역 유통한약재의 약용부위에 따른 유해중금속 분포

  • Kim, Donggyu (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Kim, Bogsoon (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Han, Eunjung (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Han, Changho (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Kim, Oukhee (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Choi, Byunghyun (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Hwang, Insook (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Chae, Youngzoo (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Kim, Minyoung (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Park, Seungkook (Institute of Life Science and Resources, Kyung Hee University)
  • 김동규 (서울시보건환경연구원) ;
  • 김복순 (서울시보건환경연구원) ;
  • 한은정 (서울시보건환경연구원) ;
  • 한창호 (서울시보건환경연구원) ;
  • 김욱희 (서울시보건환경연구원) ;
  • 최병현 (서울시보건환경연구원) ;
  • 황인숙 (서울시보건환경연구원) ;
  • 채영주 (서울시보건환경연구원) ;
  • 김민영 (서울시보건환경연구원) ;
  • 박승국 (경희대학교 생명과학대학)
  • Received : 2009.09.29
  • Accepted : 2009.10.27
  • Published : 2009.12.25

Abstract

In this study, the safety of commercial herbal medicines was evaluated by determining concentration of hazardous heavy metals. 3,152 samples (244 types) purchased by individual packing unit from market in Seoul, were analyzed using ICP-MS and mercury analyzer. As a result, the content (mg $kg^{-1}$) of Pb was higher in the above-ground part (0.92) than underground part (0.43). But in case of As and Cd contents, there is slightly higher in the underground-parts (0.26, 0.13) than the above-ground parts (0.18, 0.08). There were many herbal medicines exceeding regulatory limits of Cd comparing with other metals. The levels of Hg seemed to be different between above-ground part(0.009) and underground part (0.008) but there was no sample exceeding tolerance limits. In the comparison of imported samples with domestic herbal medicines, it was shown that Pb, As, and Hg were measured highly in the imported ones, Cd was not significantly different (t-test, p<0.05). The significant correlation was observed between Pb and As (r=0.386, p<0.01) but there was no difference in other parts. The heavy metal contamination of herbal medicines measured in total amount of respective heavy metals (mg $kg^{-1}$) was high in Flos (6.241) and Caulis (2.238), and decreased in the order of Cortex (1.634), Herba (1.154), Perithecium (0.861), Rhizoma (0.828), Radix (0.825), Fructus (0.475), and was low in Semen (0.422) (ANOVA-test, p<0.05).

Keywords

heavy metals;herbal medicines;ICP-MS

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