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The Effects of Panax Ginseng on Streptozotocin-Induced Diabetic Rats: Meta Analysis

Kook, Se-Jeong;Kim, Gun-Hee;Choi, Ki-Heon

  • Published : 2009.02.28

Abstract

The present study was carried out to summarize the effect of ginseng in the experimental diabetic rats by meta-analysis related studies. The association measure to test effect of ginseng was the mean difference(MD) between group of rats induced streptozotocin(STZ) and group of rats induced STZ treated with ginseng about the considered effect factors. The level of FI, glucose and TG were significantly reduced(< 0.01), and the level of glycogen was significantly increased by treatment with ginseng (< 0.01) After checking the indication of publication bias for the combined MDs by using the funnel plots, the anti-diabetic effects of ginseng is clearly presented in FI, glucose, TG and glycogen (< 0.05).

Keywords

Panax Ginseng;meta analysis;publication bias;trim and fill method

References

  1. Alarcon-Aguilara, F. J., Roman-Romos, R., Perez-Gutierrez, S., Aguilar Contreas, A., Contreras-Weber, C. C. and Flores-Saenz, J. L. (1998). Study of the anti-hyperglycemic effect of plants used as antidiabetics, Journal of Ethnopharmacology, 61 101-110 https://doi.org/10.1016/S0378-8741(98)00020-8
  2. Choi, K. and Kook, S. (2007a). Meta analysis by MIX program, Journal of the Korean Data Analysis Society, 9, 2425-2434
  3. Choi, K. and Kook, S. (2007b). What is the Meta Analysis? Meta Analysis using Program MIX, Free Academy, Seoul, 2-4
  4. King, H., Aubert, R. E. and Herman, W. H. (1998). Global burden of diabetes, 1995-2025: Prevalence, numerical estimates, and projections, Diabetes Care, 21, 1414-1431 https://doi.org/10.2337/diacare.21.9.1414
  5. Maries, R. J. and Fransworth, N. (1995). Antidiabetic plants and their active constituents, Phytomedicine, 2, 137-189 https://doi.org/10.1016/S0944-7113(11)80059-0
  6. Pari, L. and Umamaheswari, J. R. (2000). Antihyperglycaemic activity of Musa sapientum flowers: Effect on lipid peroxidation in alloxan diabetic rats, Phytotherapy Research, 14, 1-3 https://doi.org/10.1002/(SICI)1099-1573(200002)14:1<1::AID-PTR580>3.0.CO;2-O
  7. Sutton, A. J., Abrams, K. J., Jones, D. R., Sheldon, T. A. and Song, F. (2000). Methods for Meta-Analysis in Medical Research, John Wiley & Sons, New York, 3-13
  8. Whitehead, A. (2002). Meta-Analysis of Controlled Clinical Trials, John Wiley & Sons, New York
  9. Yajnik, C. S. (2001). The insulin resistance epidemic in India: Fetal origins, later lifestyle, or both?, Nutrition Reviews, 59, 1-9 https://doi.org/10.1111/j.1753-4887.2001.tb01898

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