Clinical Characteristics of Patients with Taste Disorders

미각 장애 환자의 임상적 특성에 관한 연구

  • Lee, Eun-Jin (Dept. of Oral Medicine & Oral Diagnosis, School of Dentistry & Dental Research Institute, Seoul National University) ;
  • Park, Won-Kyu (Dept. of Oral Medicine & Oral Diagnosis, School of Dentistry & Dental Research Institute, Seoul National University) ;
  • Nam, Jin-Woo (Dept. of Oral Medicine & Oral Diagnosis, School of Dentistry & Dental Research Institute, Seoul National University) ;
  • Yun, Jong-Il (Dept. of Oral Medicine & Oral Diagnosis, School of Dentistry & Dental Research Institute, Seoul National University) ;
  • Kho, Hong-Seop (Dept. of Oral Medicine & Oral Diagnosis, School of Dentistry & Dental Research Institute, Seoul National University)
  • 이은진 (서울대학교 치의학대학원 구강내과.진단학 교실, 치학연구소) ;
  • 박원규 (서울대학교 치의학대학원 구강내과.진단학 교실, 치학연구소) ;
  • 남진우 (서울대학교 치의학대학원 구강내과.진단학 교실, 치학연구소) ;
  • 윤종일 (서울대학교 치의학대학원 구강내과.진단학 교실, 치학연구소) ;
  • 고홍섭 (서울대학교 치의학대학원 구강내과.진단학 교실, 치학연구소)
  • Published : 2009.12.30

Abstract

There is tremendous variability in the ways patients present with taste problems. Because of complex and multifactorial etiological background, it is not simple to evaluate patients with taste disorders. Accurate assessment of patients' status by prudent, thorough history taking and symptom analysis is the most essential for exact diagnosis of taste disorders. The aim of this study was to investigate the clinical characteristics of patients with taste problems as a primary complaint. Consecutive series of 50 patients (12 males and 38 females, mean age $53.6\;{\pm}\;14.7$ years) were included for the present study. All subjects were requested to complete a comprehensive questionnaire. Clinical evaluation procedures included oral examination, interview, questionnaire analysis, panoramic radiography, blood test and measurement of salivary flow rate. The obtained results were as follows: 1. Among the patients, 36 patients (72%) complained of oral mucosal pain or burning sensation. Of these patients, 18 patients (36%) were diagnosed as burning mouth syndrome. 2. Nineteen patients (38%) complained of subjective oral dryness. The flow rate of unstimulated whole saliva was less than 0.1 mL/min in 14 patients (28%) and 17 (34%) had a stimulated whole salivary flow rate of less than 0.5 mL/min. 3. Among the types of taste disorders, hypogeusia, the most frequently reported, was found in 25 patients (50%), dysgeusia in 18 patients (36%), phantogeusia in 15 patients (30%), hypergeusia in 10 patients (20%), and ageusia in 5 patients (10%). Nineteen patients (38%) reported more than one type of taste disorder and the most frequent combination was dysgeusia + hypogeusia (n=6, 12%). 4. Based on data from the medical and dental histories and examinations, the patients were assigned to 12 probable causal categories. Taste disorders due to oral mucosal diseases and idiopathic taste disorder were the most frequent (n=9; 18%, each), followed by psychogenic taste disorder (n=8; 16%), drug-induced taste disorder (n=7; 14%), and taste disorder due to dry mouth (n=6; 12%). These 5 categories of taste disorder accounted for 78% of all cases in this study.

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