A Study on the Measurement of Heart Rate Variability using the Modified Laplacian Electrodes

수정된 라플라시안 센서를 이용한 심박변이도 측정에 관한 연구

  • 이충근 (연세대 공대 전기전자공학과) ;
  • 신항식 (연세대 공대 전기전자공학과) ;
  • 김홍래 (연세대 공대 기계공학과) ;
  • 이정환 (건국대 공대 의학공학부) ;
  • 김용준 (연세대 공대 기계공학과) ;
  • 이명호 (연세대 공대 전기전자공학과)
  • Published : 2009.05.01


Heart Rate Variability(HRV) is a parameter that represents monitoring variability of time intervals between R-peak in electrocardiography. HRV serves to various applications, such as indices of autonomic functions, prediction of cardiac sudden death, assessment of stress and emotional, etc. However, as measuring R-peak in ECG needs at least 3-electrodes, and it is inconvenient for end users. In this paper, we suggested the modified laplacian electrodes for measuring HRV at one-point, which are producted by MEMS fabrication and have the two circular electrodes on the pad. For optimal position and direction, we performed an experiment that compared with pearson correlation coefficient and the amplitude of signals, between standard lead II and proposed electrodes. We analyzed the HRV parameters, such as standard deviation of the NN interval(SDNN), high frequency(HF), low frequency(LF), LF/HF ratio. The result showed that the average correlation coefficient and amplitude are 0.967 and 0.685 mVpp at the position 2. The coeffiecient correlation between the standard HRV and proposed electrode-HRV is 0.999


Autonomic nervous assessment;Laplacian Electrodes;Heart Rate Variability


  1. Dobrev D. Petkov, et al, 'Two-electrode Low Supply Voltage Electrocardiogram Signal Amplifier,' Medical and Biological Engineering and Computing, Vol.42, pp.140-118, 2004
  2. Nicholas D. Giardino, et al.. 'Comparison of Finger to RCG in the Measurement of Heart Rate Variability,' Psychophysiology, Vol.39, pp.246-253, 2002 https://doi.org/10.1017/S0048577202990049
  3. Bin He, 'Principle and Applications of the Laplacian Electrocardiogram,' IEEE Transactions on Biomedical Engineering, Vol.16, pp.133-138, 1997 https://doi.org/10.1109/51.620505
  4. Tadahiro Asaishi, 'Measurement of ECGs and Development of an Ambulatory Device for ECG Monitoring Based on Laplacian Method,' Tokyo Denki Univ, the M.S Dissertation, 2000
  5. Chih-Cheng Lu, Peter P. Tarjan, 'Pastelss, Active, Concentric Ring Sensors for Directly Obtained Laplacian Cardiac Electrograms,' Journal of Medical and Engineering, Vol.22, pp.199-203, 2002
  6. Meir Nitzan, et al, 'The Variability of the Photoplethysmographic Signal - a Potential Method for the Evaluation of the Autonomic Nervous System,' Physiological Measurement, Vol.19, pp.93-102, 1998 https://doi.org/10.1088/0967-3334/19/1/008
  7. 최병철, '광전용적맥파를 이용한 맥파전달시간 시스템 구현 및 평가,' 공학박사학위 논문, 부산대학교, 2004
  8. Sheng Lu. et al.. 'Can Photoplthysmography Variability Serves an Alternative Approach to Obtain Heart Rate Variability Information?,' Journal of Clinical Monitoring and Computing, Vol.22, pp.23-29, 2007 https://doi.org/10.1007/s10877-007-9103-y
  9. Besio Walt, Chen Tan, 'Tripolar Laplacian electrocardiogram and moment of activation isochronal mapping,' Physiological Measurement, Vol.28, pp.515-529, 2007 https://doi.org/10.1088/0967-3334/28/5/006
  10. Pan Jaipu, Wills J. Tompkins, 'A Real-time QRS Detection Algorithm,' IEEE Transactions on Biomedical Engineering, Vol.3, pp.230-236, 1985 https://doi.org/10.1109/TBME.1985.325532
  11. HeartMath research center, 'Autonomic Assessment Report : A Comprehensive Heart Rate Variability Analysis,' HeartMath Hesearch Center, 1996
  12. John Allen, 'Photoplethysmography and its Application in Clinical Physiological Measurement,' Physiological Measurement, Vol.28, pp.R1-R39, 2007 https://doi.org/10.1088/0967-3334/28/3/R01
  13. European task force team, 'Heart Rate Variability,' European Heart Journal, pp.354-381, 1996
  14. Nitish V. Thakor and John G. Webster, 'Ground-Free ECG Recording with Two Electrodes,' IEEE Transactions on Biomedical Engineering, Vol.27, pp.699-704, 1980 https://doi.org/10.1109/TBME.1980.326595
  15. Robert Rauh, et al, 'Comparison of Heart Rate Variability and Pulse Rate Variability Detected With Photoplethysmography,' Optical Technologies in Biophysics and Medicine, SPIE, Vol.5474, pp.115-126, 2004 https://doi.org/10.1117/12.578377