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한국산 마늘에 의한 Aspergillus parasiticus의 성장 억제 효과

Inhibitory Effect of Garlic on the Growth of Aspergillus parasiticus

  • 박정영 (계명대학교 공중보건학과) ;
  • 김종규 (계명대학교 공중보건학과)
  • 발행 : 2009.04.30

초록

This study was performed to investigate the possible effect of garlic produced in Korea on the inhibition/reduction of growth of A. parasiticus, a toxigenic strain. The effect was studied using different concentrations of freeze-dried garlic in potato-dextrose agar (PDA) and/or in yeast-extract sucrose (YES) broth at $25^{\circ}C$ for 15 days. While inhibition of the fungal growth due to increasing the concentration of garlic was observed, the more remarkable effect was observed on the ninth day. Reduction of fungal diameter as a result of addition of garlic on PDA was observed to range between 3.4% to 20.1 % while reduction of mycelial weight in YES broth ranged from 9.9% to 30.5%. The 0.5% and 1.0% concentrations of garlic significantly reduced fungal diameter in PDA on the 9th day, while 0.1 %, 0.5%, and 1.0% concentrations of garlic significantly reduced the mycelial weight in YES broth (p<0.05). Dose-response relationships were observed between the concentration of garlic and inhibition of growth both in solid culture and in liquid culture. This study indicates that garlic could be an effective inhibitor at a human consumption level of the growth of A. parasiticus. More research is needed to study the inhibitory effects of the main active component of garlic.

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피인용 문헌

  1. A Study of the Histological Effects of Garlic Extract in a Liver-damage Rat Model vol.36, pp.4, 2010, https://doi.org/10.5668/JEHS.2010.36.4.279