- Volume 39 Issue 12
DOI QR Code
Effects of Onion Peel Extracts on Blood Circulation in Male Smokers
양파껍질추출물의 섭취가 남성 흡연자의 혈행개선에 미치는 효과
- Lee, Hye-Jin (Dept. Food & Nutrition, Changwon National University) ;
- Lee, Kyung-Hea (Dept. Food & Nutrition, Changwon National University) ;
- Cha, Young-Jun (Dept. Food & Nutrition, Changwon National University) ;
- Park, Eun-Ju (Dept. of Food & Nutrition, Kyungnam University) ;
- Shin, Min-Jeong (Dept. of Food & Nutrition, Korea University)
- 이혜진 (창원대학교 식품영양학과) ;
- 이경혜 (창원대학교 식품영양학과) ;
- 차용준 (창원대학교 식품영양학과) ;
- 박은주 (경남대학교 식품영양학과) ;
- 신민정 (고려대학교 식품영양학과)
- Received : 2010.09.14
- Accepted : 2010.11.02
- Published : 2010.12.31
A controlled and double blinded trial was performed to evaluate the effects of OPE supplementation on blood circulation in healthy male smokers. The study population consisted of 92 healthy male smokers aged
- Choi SK, Choi HS. 2004. Purification and characterization of an anticoagulant from corn silk. J Korean Soc Food Sci Nutr 33: 1262-1267. https://doi.org/10.3746/jkfn.2004.33.8.1262
- Ministry of Health and Welfare. 2008. The Korea National Health & Nutrition Examination Survey.
- Korean national statistical office. Available at http://kosis. kr/gen_etl/start.jsp? orgId=101&tblId=DT_1B34E13&conn_ path=I2&path. Assessed August 18, 2010.
- Lee HJ. 2009. Hypolipidemic effect of supplemented onion xtract in participants with borderline high cholesterol level. MS Thesis. Changwon University, Gyeongnam, Korea.
- Yun EJ. 2003. Effects of exercise on blood coagulation and anticoagulants. MS Thesis. Sungkyunkwan University, Seoul, Korea.
- Noh KH, Park CM, Jang JH, Shin JH, Cho MK, Kim JO, Song YS. 2009. Effects of nattokinase fibrinol supplementation on fibrinolysis and atherogenesis. J Life Science 19: 289-298. https://doi.org/10.5352/JLS.2009.19.2.289
- Lee JH, Kim SH. 1995. Effect of the long-term ginseng intakes on serum lipids profile and hemostatic factors in human. Korean J Nutr 28: 862-871.
- Chung JH. 2003. Establishment of functionality evaluation system for the homeostasis of health functional food. Available at http://kfda.go.kr/index.kfda?mid=102&seq=709 &cmd. Assessed August 18, 2010.
- Ahn HS, Lee GJ, Kim NY. 2002. Studies on lipid intake, serum lipid profiles and serum fatty acid composition in college women who smoke. Korean J Community Nutr 7: 102-110.
- Hwang KH, Lee DS, Lee BI, Lee JS, Lee HY, Chung JK, Lee MC. 2004. Evaluation of endothelium-dependent myocardial perfusion reserve in healthy smokers; cold pressor test using H2(15)O PET. Korean J Nucl Med 38: 21-29.
- Barua RS, Ambrose JA, Srivastava S, DeVoe MC, Eales-Reynolds LJ. 2003. Reactive oxygen species are involved in smoking-induced dysfunction of nitric oxide biosynthesis and upregulation of endothelial nitric oxide synthase: an in vitro demonstration in human coronary artery endothelial cells. Circulation 107: 2342-2347. https://doi.org/10.1161/01.CIR.0000066691.52789.BE
- Rhim TJ, Lim SC. 2005. The hepatoprotective and antioxidative effects of onion (Allium cepa) extracts in rat hepatocyte primary culture. Korean J Plant Res 18: 470-478.
- Hwang KH, Jung LH, Cho NC, Yoo YK, Park PS, Noh YH, Seo HS, Noh YH, Seo HS, Noh IO. 2003. The effect of concentrated onion juice in a body composition, serum electrolytes and lipids levels on hyperlipidemia. Korean J Food & Nutr 16: 35-45.
- Westrope KL, Miller RA, Wilson RB. 1982. Vitamin E in a rabbit model of endogeneous hypercholesterolemia and atherosclerosis. Nutr Rep Int 25: 83-88.
- Mazur A, Nassir F, Gueux E, Moundras C, Bellanger J, Grolier P, Rock E, Rayssiguier Y. 1996. Diets deficient in selenium and vitamin E effect plasma lipoprotein and apolipoprotein concentrations in the rat. Br J Nutr 76: 899-907. https://doi.org/10.1079/BJN19960096
- Hertog MGL, Feskens EJM, Hollman PCH, Katan MB, Kromhout D. 1993. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen elderly study. Lancet 342: 1007-1011. https://doi.org/10.1016/0140-6736(93)92876-U
- Lakhanpal P, Rai DK. 2007. Quercetin: a versatile flavonoid. IJMU 2: 22-37.
- Ra KS, Suh HJ, Chung SH, Son JY. 1997. Antioxidant activity of solvent extract from onion skin. Korean J Food Sci Technol 29: 595-600.
- Jang JR, Lim SY. 2009. Effects of onion flesh and peel on chemical components, antioxidant and anticancer activities. J Life Science 19: 1598-1604. https://doi.org/10.5352/JLS.2009.19.11.1598
- Lee KH, Kim YH, Park E, Hwang HJ. 2008. Effect of onion powder supplementation on lipid metabolism in high fatcholesterol fed SD rats. J Food Sci Nutr 13: 71-76. https://doi.org/10.3746/jfn.2008.13.2.071
- de Whalley CV, Rankin SM, Hoult JR, Jessup W, Leake DS. 1990. Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages. Biochem Pharmacol 39: 1743-1750. https://doi.org/10.1016/0006-2952(90)90120-A
- Verma AK, Johnson JA, Gould MN, Tanner MA. 1988. Inhibition of 7,12-dimethylbenz(a)anthracene-and N-nitrosomethylurea- induced rat mammary cancer by dietary flavonol quercetin. Cancer Res 48: 5754-5758.
- Kim JH. 1997. Anti-bacterial action of onion (Allium cepa L.) extracts against oral pathogenic bacteria. J Nihon Univ Sch Dent 39: 136-141. https://doi.org/10.2334/josnusd1959.39.136
- Lee KH, Kim YH, Park E, Cho SR. 2008. Study on dietary habit and effect of onion powder supplementation on serum lipid levels in early diagnosed hyperlipidemic patients. J Korean Soc Food Sci Nutr 37: 561-570 https://doi.org/10.3746/jkfn.2008.37.5.561
- Herrmann K. 1976. Flavonoids and flavones in food plants, a review. Int J Food Sci Tech 11: 433-448. https://doi.org/10.1111/j.1365-2621.1976.tb00743.x
- Bang HA, Cho JS. 1998. Antioxidant effects on various solvent extracts from onion peel and onion flesh. J Korean Diet Assoc 4: 14-19.
- Shim YY, An JH, Cho WD, Chun H, Kim KI, Cho HY, Yang HC. 2002. Inhibitory mechanism of blood coagulation and in vivo anticoagulant activities of polysaccharides isolated from codium fragile. J Korean Soc Food Sci Nutr 31: 917-923. https://doi.org/10.3746/jkfn.2002.31.5.917
- Mueller RL, Scheidt S. 1994. History of drugs for thrombotic disease. Discovery, development, and directions for the future. Circulation 89: 432-449. https://doi.org/10.1161/01.CIR.89.1.432
- Mustard JF, Packham MA. 1970. Factors influencing platelet function: adhesion, release and aggregation. Pharmacol Rev 22: 97-187.
- Friedman GD, Dales LG, Ury HK. 1979. Mortality in middled-aged smokers and nonsmokers. N Engl J Med 300: 213-217. https://doi.org/10.1056/NEJM197902013000501
- McGill HC Jr. 1979. Potential mechanisms for the augmentation of atherosclerosis and atherosclerotic disease by cigarette smoking. Prev Med 8: 390-403. https://doi.org/10.1016/0091-7435(79)90016-1
- Craig WY, Palomaki GE, Haddow JE. 1989. Cigarette smoking and serum lipid and lipoprotein concentrations: an analysis of published data. BMJ 298: 784-788. https://doi.org/10.1136/bmj.298.6676.784
- Bronte-Stewart B. 1961. Cigarette smoking and ischaemic heart disease. BMJ 1: 379-384. https://doi.org/10.1136/bmj.1.5223.379
- Gordon T, Kannel WB, McGee D, Dawber TR. 1974. Deaths and coronary attacks in men after giving up cigarette smoking. Lancet 2: 1345-1348.
- Nam KH, Baik HW, Chio TY, Yoon SG, Park SW, Joung HJ. 2007. Effects of ethanol extract of onion on the lipid profiles in patients with hypercholesterolemia. Korean J Nutr 40: 242-248.
- Kim SK, Kim MK. 2004. Effect of dried powders of ethanol extracts of onion flesh and peel on lipid merabolism, antioxidative and antithrombogenic capacities in 16-month-old rats. Korean J Nutr 37: 623-632.
- Gillis A, Perry A. 1991. The relationships between physical activity and health-promoting behaviours in mid-life women. J Adv Nurs 16: 299-310. https://doi.org/10.1111/j.1365-2648.1991.tb01653.x
- Kim OS. 2004. Drinking, smoking, self-rated health, and health supplement foods use in adult men. Nurs Sci 16: 1-8.
- Idler EL, Angel RJ. 1990. Self-rated health and mortality in the NHANES-Ⅰ epidemiologic follow-up study. Am J Public Health 80: 446-452. https://doi.org/10.2105/AJPH.80.4.446
- Jang MJ, Rhee SJ, Cho SH, Woo MH, Choi JH. 2006. A study on the antioxidative, anti-inflammatory and antithrombogenic effects of Zanthoxylum piperitum DC extract. J Korean Soc Food Sci Nutr 35: 21-27. https://doi.org/10.3746/jkfn.2006.35.1.021
Moon CH, Jung YS, Kim MH, Lee SH, Baik EJ, Park SW.
2000. Mechanism for antiplatelet effect of onion: AA release
inhibition, thromboxane A2 synthase inhibition and
$TXA_2/PGH_2 $receptors blockade. Prostaglandins Leukot Essent Fatty Acids 62: 277-284. https://doi.org/10.1054/plef.2000.0155
- Lanza F, Beretz A, Stierlé A, Corre G, Cazenave JP. 1987. Cyclic nucleotide phosphodiesterase inhibitors prevent aggregation of human platelets by raising cyclic AMP and reducing cytoplasmic free calcium mobilization. Thromb Res 45: 477-484. https://doi.org/10.1016/0049-3848(87)90310-0
- Cho EY, Bae SJ, Yoo HJ, Chang YS, Lee JH. 2003. Effect of obesity on blood coagulation factors. Abstract No 128 presented at Annual Meeting of the Korean Society of Nutrition. Seoul,Korea.
- Anti-inflammatory Effect of Onion (Allium cepa) Peel Hot Water Extract in vitro and in vivo vol.30, pp.4, 2015, https://doi.org/10.7841/ksbbj.2015.30.4.148
- Combined effects of electron beam irradiation and addition of onion peel extracts and flavoring on microbial and sensorial quality of pork jerky vol.39, pp.3, 2012, https://doi.org/10.7744/cnujas.2012.39.3.341
- Effect of Onion Peel Extracts on Blood Lipid Profile and Blood Coagulation in High Fat Fed SD Rats vol.24, pp.3, 2011, https://doi.org/10.9799/ksfan.2011.24.3.442
- Productivity and quality characteristics of onions applied with defective onion and purslane extracts during cultivation vol.49, pp.6, 2015, https://doi.org/10.14397/jals.2015.49.6.37