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Fabrication of Porous Calcium Phosphate by Using a Pre-Form of Nature Material

자연물의 미세구조를 활용한 다공성 인산칼슘 제조

  • Received : 2010.03.19
  • Accepted : 2010.05.10
  • Published : 2010.05.31

Abstract

Porous calcium phosphates were successfully fabricated by using a cuttlefish bone. The cuttlefish bone, which is composed of $CaCO_3$, showed a special porous microstructure containing uniform-sized voids. In this study, the pre-forms infiltrated distilled phosphoric acid were sintered at $1200^{\circ}C$ in an air atmosphere. The porous microstructure of the pre-forms was kept their original pattern after sintering with a synthesis of calcium phosphate. The obtained porous calcium phosphate, sintered at $1200^{\circ}C$ for 3 h at 17% concentration of phosphoric acid, showed uniform open pores of 150 ${\mu}m$ in size and $\beta$-TCP phase in the XRD patterns. Above 16% concentration, CaO phase, derived from the decomposition of $CaCO_3$, decreased gradually in the sintered samples, and the measured Ca/P ratios of the samples prepared from 16% and 18% concentration were 1.67 and 1.43, which are close to stoichiometric HA (1.66) and $\beta$-TCP (1.50).

Keywords

Cuttlefish bone;Calcium phosphate;Phosphoric acid;Porous microstructure

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Cited by

  1. Porous Biphasic Calcium Phosphate Scaffolds from Cuttlefish Bone vol.94, pp.8, 2011, https://doi.org/10.1111/j.1551-2916.2011.04404.x
  2. Biomedical Materials for Regenerating Bone Tissue Utilizing Marine Invertebrate vol.48, pp.1, 2015, https://doi.org/10.5657/KFAS.2015.0001
  3. Hydroxyapatite from Cuttlefish Bone: Isolation, Characterizations, and Applications vol.23, pp.4, 2018, https://doi.org/10.1007/s12257-018-0169-9

Acknowledgement

Supported by : 목포대학교