Affecting Factors on Left Ventricle Ejection Fraction Measured using 64-slice MDCT

64 절편 MDCT를 이용한 심장CT에서 측정된 좌심실 구혈률에 영향을 미치는 요인

  • 강영한 (대구가톨릭대학교병원 영상의학과) ;
  • 김경욱 (대구가톨릭대학교병원 영상의학과) ;
  • 조광호 (대구가톨릭대학교 방사선학과)
  • Published : 2010.02.28


This study was to analysis what factors could affect left ventricle ejection fraction(LVEF) using 64-slice multidetector CT. 164 patients(84 men, 80 women) had a cardiac CT in this study, and their blood pressure, body mass index(BMI), heart rate(HR) measured. LVEF was 52.00${\pm}$18.95% in below 25kg/$m^2$, 59.50${\pm}$16.05% in above 25kg/$m^2$ of BMI. LVEF was 57.26${\pm}$17.84% in normal blood pressure group(NBPG), 49.95${\pm}$17.63 in hypertension group(HG). LVEF was 60.76${\pm}$17.26 in below 60 beats/min, 54.14${\pm}$16.56 in 60-70 beats/min, 50.83${\pm}$20.56 in above 70 beats/min of HR. LVEF was negatively correlated with age, HR(r=-0.283 p<0.05, r=-0.231 p<0.05. respectively). And LVEF was positively correlated with BMI(r=0.228 p<0.05). A measurement of LVEF at cardiac CT by using MDCT may be considered to age, blood pressure, heart rate and BMI.


64-slice Multidetector CT;Left Ventricle Ejection Fraction;Body Mass Index;Heart Rate


  1. L. Pilote, J. Silberberg, R. Lisbona, and A. Sniderman, "Prognosis in patients with low left ventricular ejection fraction after myocardial infarction. Importance of exercise capacity," Circulation, Vol.80, No.6, pp.1636-1641, 1989.
  2. K. Hina, S. Kusachi, and K. Iwasaki, "Progression of left ventricular enlargement in patients with hypertrophic cardiomyopathy: incidence and prognostic value," Clin Cardiol, Vol.16, No.5, pp.403-407, 1993.
  3. P. Garot, O. Pascal, and M. Simon, "Impact of microvascular integrity and local viability on left ventricular remodelling after reperfused acute myocardial infarction," Heart, Vol.89, No.4, pp.393-397, 2003.
  4. T. Sharir, G. Germano, and P. B. Kavanagh, "Incremental prognostic value of post-stress left ventricular ejection fraction and volume by gated myocardial perfusion single photon emission computed tomography," Circulation, Vol.100, No.10, pp.1035-1042, 1999.
  5. Y. W. Wu, M. Tadamuro, and M. Yamamuro, "Estimation of global and regional cardiac function using 64-slice computed tomography: a comparison study with echocardiography, gated- SPECT and cardiovascular magnetic resonance," Int J Cardiol, Vol.128, No.1, pp.69-76, 2008.
  6. A. K. Chung, S. R. Das, and D. Leonard, "Women have higher left ventricular ejection fractions than men independent of differences in left ventricular volume: the Dallas Heart Study," Circulation, Vol.113, No.12, pp.1597-1604, 2006.
  7. A. T. Yamada, Campos Neto Gde C., and Soares J. Jr, "Gender difference in ventricular volumes and left ventricle ejection fraction estimated by myocardial perfusion imaging: comparison of Quantitative Gated SPECT(QGS) and Segami software programs," Arg Bras Cardiol, Vol.88, No.3, pp.285-290, 2007.
  8. S. Dobala, S. Crugnale, D. Yang, and M. F. Di Cali, "Effect of body mass index on left ventricular cavity size and ejection fraction," Am J Cardiol. Vol.97, No.5, pp.725-729, 2006.
  9. B. D. Powell, M. M. Redfield, K. A. Bvbee, W. K. Freeman, and C. S. Rihal, "Association of obesity with left ventricular remodelling and diastolic dysfunction in patients without coronary artery disease," Am J Cardiol, Vol.98, No.1, pp.116-120, 2006.
  10. World Health Organization western pacific region, "The asia-pacific perspectives; redefining obesity and its treatment," 2000.
  11. D. Mele, M. Campana, and M. Sclavo, "Impact of tissue harmonic imaging in patients with distorted left ventricles: improvement in accuracy and reproducibility of visual, manual and automated echocardiographic assessment of left ventricular ejection fraction," Eur J Echocardiogr, Vol.4, No.1, pp.59-67, 2003.
  12. 강재황, 박은숙, 강병선, 임현옥, 최동주, 이근우 등, “정상 한국인에서 게이트혈액풀스캔을 이용한 좌심실 심기능지표들의 분석”, 대한핵의학회지, 제28권, 제1호, pp.52-61, 1994.
  13. B. Berkalp, V. Cesur, D. Corapcioglu, C. Erol, and N. Baskal, "Obesity and left ventricular diastolic dysfunction," Int J Cardiol, Vol.52, No.1, pp.23-26, 1995.
  14. F. H. Messerli, K. Sundugaard-Riise, E. Reisiu, G. Dreslinski, F. G. Dunn, and E. Frohlich, "Disparate cardiovascular effects of obesity and arterial hypertension," Am J Med, Vol.74, No.5, pp.808-812, 1983.
  15. J. P. Coffev and J. C. Hill, "Gated single photon emission tomography MIBI stress perfusion imaging for assessing cardiac output and index in obese and non-obese patients," Ir J Med Sci, Vol.176, No.4, pp.297-303, 2007.
  16. 강덕희, "고혈압환자에서 도플러 심초음파를 이용한 좌우심실 이완기능에 관한 연구", 이화여자대학교 대학원 석사학위논문, 1991.
  17. R. O. Bonow, E. Lakatos, B. J. Maron, and S. E. Epstein, "Serial long-term assessment of the natural history of asymptomatic patients with chronic aortic regurgitation and normal left ventricular systolic function," Circulation, Vol.84, No.4, pp.1625-1635, 1991.
  18. R. J. Rodeheffer, G. Gerstenblith, L. C. Becker, J. L. Fleg, M. L. Weisfeldt, and E. G. Lakatta, "Exercise cardiac output is maintained with advancing age in healthy human subjects: Cardiac dilatation and increased stroke volume compensate for a diminished heart rate," Circulation, Vol.69, No.2, pp.203-213, 1984.
  19. T. Mochizuki, K. Murase, and H. Higashino, "Two-and three dimensional CT ventriculography: a new application of helical CT", AJR, Vol.174, No.1, pp.203-208, 2000.
  20. M. L. Weisfieldt, "Left ventricular function, The aging heart," New York Raven Press, pp.297-316, 1980.