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Characteristics of tamiflu occurrence in surface water using LC/MS/MS

LC/MS/MS를 이용한 하천수 중 항바이러스제 타미플루 잔류 특성

  • Shin, Sun-Kyoung (National Institute of Environmental Research of Environmental Research, Chemical Behavior Research Division) ;
  • Kang, Young-Yeul (National Institute of Environmental Research of Environmental Research, Chemical Behavior Research Division) ;
  • Park, Jin-Soo (National Institute of Environmental Research of Environmental Research, Chemical Behavior Research Division) ;
  • Koo, So-Hyun (National Institute of Environmental Research of Environmental Research, Chemical Behavior Research Division) ;
  • Hwang, Seung-Ryul (National Institute of Environmental Research of Environmental Research, Chemical Behavior Research Division) ;
  • Kim, Woo-Il (National Institute of Environmental Research of Environmental Research, Chemical Behavior Research Division) ;
  • Song, Ki-Bong (National Institute of Environmental Research of Environmental Research, Chemical Behavior Research Division) ;
  • Kim, Young-Hee (National Institute of Environmental Research of Environmental Research, Chemical Behavior Research Division) ;
  • Kim, Tae-Seung (National Institute of Environmental Research of Environmental Research, Drinking Water Research Division) ;
  • Han, Jin-Suk (National Institute of Environmental Research of Environmental Research, Chemical Behavior Research Division)
  • 신선경 (국립환경과학원 환경건강위해성연구부 화학물질거동연구과) ;
  • 강영렬 (국립환경과학원 환경건강위해성연구부 화학물질거동연구과) ;
  • 박진수 (국립환경과학원 환경건강위해성연구부 화학물질거동연구과) ;
  • 구소현 (국립환경과학원 환경건강위해성연구부 화학물질거동연구과) ;
  • 황승률 (국립환경과학원 환경건강위해성연구부 화학물질거동연구과) ;
  • 김우일 (국립환경과학원 환경건강위해성연구부 화학물질거동연구과) ;
  • 송기봉 (국립환경과학원 환경건강위해성연구부 화학물질거동연구과) ;
  • 김영희 (국립환경과학원 환경건강위해성연구부 화학물질거동연구과) ;
  • 김태승 (국립환경과학원 물환경연구부 먹는물연구과) ;
  • 한진석 (국립환경과학원 환경건강위해성연구부 화학물질거동연구과)
  • Received : 2010.02.19
  • Accepted : 2010.03.31
  • Published : 2010.04.25

Abstract

Oseltamivir carboxylate (OC) and Oseltamivir ethylester (OE) were analyzed to evaluate the environmental distribution in pandemic season in Korea. The detected concentration of OE was the range of $0.008\sim0.087\;{\mu}g/L$, and OC was the range of $0.029\sim0.287\;{\mu}g/L$. The detected concentration of OC in this study was two times higher than reported concentration of OC in river water in Japan. But, these analytical results cannot be directly compared to the previous reported concentration, because of the different sampling period.

Keywords

tamiflu;oseltamivir ethylester phosphate;oseltamivir ethylester;oseltamivir carboxylate;LC/MS/MS

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