A Review of Etiopathogenesis of Burning Mouth Syndrome

구강작열감증후군의 병인론과 병태생리에 대한 고찰

  • Lim, Hyun-Dae (Department of Oral medicine, School of Dentistry, Wonkwang University Wonkwang Dental Research Institute) ;
  • Kang, Jin-Kyu (Department of Oral medicine, School of Dentistry, Wonkwang University Wonkwang Dental Research Institute) ;
  • Lee, You-Mee (Department of Oral medicine, School of Dentistry, Wonkwang University Wonkwang Dental Research Institute)
  • 임현대 (원광대학교 치과대학 구강내과학 교실 및 원광치의학 연구소) ;
  • 강진규 (원광대학교 치과대학 구강내과학 교실 및 원광치의학 연구소) ;
  • 이유미 (원광대학교 치과대학 구강내과학 교실 및 원광치의학 연구소)
  • Received : 2010.01.12
  • Accepted : 2010.02.17
  • Published : 2010.03.30


Burning mouth syndrome(BMS) is a chronic oral pain and a symptom complex disorder usually unaccomplished by mucosal lesion or other clinical and laboratory signs of organic disease. BMS is characterized by a spontaneous burning sensation that mainly affects middle-aged and postmenopausal women. The etiology of BMS is poorly understood even though evidence for a possible neuropathic pathogenesis. BMS cause from various local or systemic factor, including nutritional deficiencies, hormonal change, local infection, dental procedure, dry mouth, medication and systemic disease including diabetes mellitus. Many studies suggest peripheral alteration in sensory of trigeminal nerve system. BMS patients with supertaster indicates pathologies of central and peripheral nerve system induced by an alteration in the taste system at the level of chorda tympani and glossopharyngeal nerve. The author discuss our current understanding of etiology and pathogenesis of BMS that refered chronic oral pain.


Supported by : 원광대학교


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