Comparative study of wound healing in canine stomach with CO2 laser and scalpel incisions

CO2 레이저와 scalpel을 이용한 위 절개 시 개에서의 창상 치유 평가

  • Lee, Jae-Yeon (College of Veterinary Medicine, Chungnam National University) ;
  • Hwang, You-Sun (College of Veterinary Medicine, Chungnam National University) ;
  • Kim, Han-Kyul (College of Veterinary Medicine, Chungnam National University) ;
  • Choi, Hyun-Suk (College of Veterinary Medicine, Chungnam National University) ;
  • Jeong, Seong-Mok (College of Veterinary Medicine, Chungnam National University) ;
  • Cho, Sung-Whan (College of Veterinary Medicine, Chungnam National University) ;
  • Park, Chang-Sik (Division of Animal Science & Resources, Research Center for Transgenic Cloned Pigs, Chungnam National University) ;
  • Kim, Myung-Cheol (College of Veterinary Medicine, Chungnam National University)
  • 이재연 (충남대학교 수의과대학) ;
  • 황유선 (충남대학교 수의과대학) ;
  • 김한결 (충남대학교 수의과대학) ;
  • 최현석 (충남대학교 수의과대학) ;
  • 정성목 (충남대학교 수의과대학) ;
  • 조성환 (충남대학교 수의과대학) ;
  • 박창식 (충남대학교 동물자원학부, 형질전환 복제돼지 연구센터) ;
  • 김명철 (충남대학교 수의과대학)
  • Accepted : 2010.06.07
  • Published : 2010.06.30

Abstract

The objective of this study was to compare wound healing in stomach with $CO_{2}$ laser and scalpel incision by measuring the extent of bleeding, the ease of gastric incision, incision time, degree of adhesion and wound healing degree in dogs. Sixteen healthy dogs were used. Two symmetrical incisions were made in ventral aspect of the stomach between the greater and lesser curvatures were made with scalpel and 0.2 mm spot diameter $CO_{2}$ laser (8W, continuous wave) in sixteen dogs. And then each wound was closed with absorbable suture in a two-layer inverting seromuscular pattern. At 3, 7, 14 and 21 days after initial wounding, each wound was taken for histological observation. On surgery, the extent of bleeding, the ease of incision and incision time showed significant differences between the groups. The $CO_{2}$ laser provided better hemostasis (p < 0.05) and smaller postoperative adhesion compared with the scalpel. However, the scalpel produced faster speed of incision and was easier to handle than the $CO_{2}$ laser (p < 0.05). Although there was no considerable difference between the two groups in histological observation, necrosis and calcium deposit tended to be larger in the $CO_{2}$ laser than in the scalpel.

Acknowledgement

Supported by : 한국연구재단

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