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Electrophysiological Features of Diabetic Polyneuropathy: Motor Nerve Conduction Studies

당뇨병성다발신경병증의 전기생리학적 특징: 운동신경전도검사

  • 강지혁 (경운대학교 임상병리학과) ;
  • 이윤섭 (경운대학교 작업치료학과)
  • Received : 2010.08.23
  • Accepted : 2010.10.06
  • Published : 2010.10.28

Abstract

Nerve conduction studies (NCS) are the most objective measure of nerve function and essential for the diagnosis of sub-clinical neuropathy in diabetes mellitus and diabetic polyneuropathy (DPN). This study evaluates the characteristic of electrophysiological abnormalities in DPN. Electrodiagnostic data from 120 patients with diabetic polyneuropathies and 77 control subjects were reviewed. Motor nerve conduction velocities (MNCV), distal motor latencies (DML), compound muscle action potential (CMAP) amplitudes, No potential frequency and conduction block were analyzed. Data were normalized based on normative reference values, and the proportion of nerves with abnormal values in the lower and upper limbs were evaluated. DPN was systemic demyelinating peripheral polyneuropathy and more severe abnormal nerve conduction was found in lower limbs than in upper limbs. The abnormal degree was more severe in peroneal nerve. It was no statistically significant difference of conduction block in control and DPN group. Our findings suggest that DPN had more common and severe peroneal nerve involvement in the motor nerve conduction studies (MNCS). These findings have important implications for the electrophysiological evaluation of DPN.

Keywords

Diabetic Polyneuropathy;Motor Nerve Conduction Studies;Peroneal Nerve

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