A Review of Burning Mouth Disorders

구강작열감질환에 관한 고찰 및 의료분쟁 증례보고

  • Hur, Yun-Kyung (Department of Oral Medicine, School of Dentistry, Kyungpook National University) ;
  • Jung, Jae-Kwang (Department of Oral Medicine, School of Dentistry, Kyungpook National University) ;
  • Choi, Jae-Kap (Department of Oral Medicine, School of Dentistry, Kyungpook National University)
  • 허윤경 (경북대학교 치의학전문대학원 구강내과학교실) ;
  • 정재광 (경북대학교 치의학전문대학원 구강내과학교실) ;
  • 최재갑 (경북대학교 치의학전문대학원 구강내과학교실)
  • Received : 2010.09.10
  • Accepted : 2010.09.20
  • Published : 2010.09.01


Burning mouth disorders (sometimes referred to as burning mouth syndrome) are characterized by a burning sensation in the tongue or other oral sites, usually in the absence of clinical and laboratory findings. Affected patients often present with multiple oral complaints, including burning, dryness and taste alterations. Burning mouth complaints are reported more often in women, especially after menopause. Typically, patients awaken without pain, but report increasing symptoms through the day and into the evening. Conditions that have been reported in association with burning mouth syndrome include chronic anxiety or depression, various nutritional deficiencies, diabetes and changes in salivary function. However, these conditions have not been consistently linked with the syndrome, and their treatment has had little impact on burning mouth symptoms. Recent studies have pointed to dysfunction of several cranial nerves associated with taste sensation as a possible cause of burning mouth disorders. The most common central mechanism that likely explains burning mouth disorders is a centrally mediated continuous neuropathic pain. Given in low dosages, benzodiazepine, tricyclic antidepressants or anticonvulsants may be effective in patients with burning mouth disorders.


  1. Grushka M.:Clinical features of burning mouth syndrome. Oral Surg Oral Med Oral Pathol, 1987:63(1):30-36. https://doi.org/10.1016/0030-4220(87)90336-7
  2. Klasser GD, Fischer DJ, Epstein JB.:Burning mouth syndrome ; recognition, understanding, and management. Oral Maxillofac Surg Clin North Am, 2008:20(2):255-271. https://doi.org/10.1016/j.coms.2007.12.012
  3. Jeffrey P. Okeson.:Bell's orofacial pains ; The clinical management of orofacial pain. 6th ed., 2005, Quintessence Publishing Co, Inc, pp 253-255, 493-495.
  4. Scala A, Checchi L, Montevecchi M, Marini I, Giamberardino MA.:Update on burning mouth syndrome ; overview and patient management. Crit Rev Oral Biol Med, 2003:14(4):275-291. https://doi.org/10.1177/154411130301400405
  5. Piedad S, Glenn T. Clark.:Burning mouth syndrome: An update on diagnosis and treatment methods. CDA Journal, 2006:34(8):611-622.
  6. Crispian Scully.:Oral and Maxillofacial medicine. 2nd ed., Philadelphia, 2008, Churchill livingstone Elsevier, pp. 171-176.