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Association between cardiovascular disease and periodontal disease prevalence

치주질환에 의한 심장질환 발생의 관련성

  • Jeong, Mi-Ae (Department of Dental Hygiene, Kangwon National University) ;
  • Kim, Jee-Hee (Department of Emergency Medical Technology, Kangwon National University)
  • 정미애 (강원대학교 치위생학과) ;
  • 김지희 (강원대학교 응급구조학과)
  • Received : 2011.09.02
  • Accepted : 2011.11.15
  • Published : 2011.12.31

Abstract

Periodontal disease is a common inflammatory disorder that is being considered as a risk factor for atherosclerotic complication. Recent epidemiological evidence also supports that its potential association with increased blood pressure levels and hypertensive prevalence. Data from cross-sectional studies suggest that in hypertensive patients periodontal disease may enhance the risk and degree of target organ damage. So dental infections have been associated with cardiovascular diseases. There are potential pathophysiologic links between hypertension and periodontits. The role of the inflammatory pathway include C-reactive protein(CRP). CRP is an inflammatory mediator that has been shown to predict the development of hypertension independently of baseline BP and traditional risk factors, has been consistently reported as at least mildly elevated in patients with periodontal disease. Reactive oxygen species produced by locally infiltrating neutrophils participate in periodontal tissue destruction. Periodontits can lead to inflammatory responses in the atrial myocardium, which disturbs the structural and electrophysiologic properties of the atrium and facilitates atrial fibrillation in the animal experiment.