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The Behavior of Acute Febrile Illness with Incidence the Fall Mixed Infection

가을철 유행하는 급성열성질환의 혼합감염 양상

  • 오혜종 (조선대학교 일반대학원 보건학과/한려대학교 임상병리학과) ;
  • 윤현 (조선대학교 일반대학원 보건학과/한려대학교 임상병리학과) ;
  • 최성우 (조선대학교 일반대학원 보건학과)
  • Received : 2012.09.26
  • Accepted : 2012.10.31
  • Published : 2012.12.28

Abstract

In this study, for behavior clinical signs and blood tests when autumn sudden fevered disease, Tsutsugamushi Disease is Single infected with mixing hemorrhagic fever with renal syndrom.221 positive patients, who have antibody titer more than 1:80 in serologic examination of Tsutsugamushi Disease in a general hospital, Jeollanam-do province, were adopted as a Analysis. in respect of frequency. Single infection patients of Tsutsugamushi Disease were 183 and mixed infection patients with Hemorrhagic Fever with Renal Syndrome were 38. In respect of age, patients over the 70's were mostly infected. In respect of sex, male patients were 70(31.7%) and female patients were 151(66.8%) Women were more infected than men. In respect of outbreak time, the more than 70% disease occurrence of all was charged in October and November and it also occurred in spring. In the clinical signs, fever(p=0.028), urtication(p=0.000) and muscle pain(p=0.000) of mixed infection was more higher than single infection. And in the blood tests, AST(p=0.000), ALT(p=0.000), blood urea nitrogen(p=0.002), total bilirubin(p=0.000) value of mixed infection was more higher than single infection.

Keywords

Tsutsugamushi Disease;Hemorrhagic Fever Renal Syndrome

References

  1. W. George and P. Philippe, "Scrub typhus and tropical rickettsioses," Current Opinion in Infectious Diseases, Vol.16, No.5, pp.429-436, 2003. https://doi.org/10.1097/00001432-200310000-00009
  2. 윤인숙, 권세영, "알레르기 환자에서 Immunoglobulin E와 Eosinophil count 및 Allergen과의 관련성," 한국콘텐츠학회, 한국콘텐츠학회논문지, 제9권, 제4호, pp.236-246, 2009. https://doi.org/10.5392/JKCA.2009.9.4.236
  3. US Army Med, "Two Strains of Rickettsia tsutsugamushi were isolated from patients," Service Graduate School Quartery Report, pp.122-128, 1953.
  4. A. D. Munro-Faure, R. Andrew, and G. A. Missen, J. Mackay-Dick, "Scrub typhus in Korea," J R Army Med Corps, Vol.97, No.4, pp.227-229, 1951.
  5. M. Tamano, H. K. Michel, and M. M. James, O. Ken, O. Takaaki, T. Hiroshi, "Evaluation of national tsutsugamushi disease surveillance - Japan," 2000, Jpn J, Infect Dis, Vol.55, No.6, pp.197-203, 2002.
  6. 김동민, "쯔쯔가무시병의 임상 특징과 진단", 대한감염학회, 제41권, 제6호, pp.315-322, 2009. https://doi.org/10.3947/ic.2009.41.6.315
  7. http://www.cdc.go.kr/
  8. H. K. Lee, H. W. Lee, C. Calisher, and C. Schmaljohn, "Manual of Hemorrha-gic fever with renal syndrome and hantavirus pul-monary syndrome," Seoul, ASAN Institute for Life Sciences, Vol.39, 1999.
  9. 송현제, 이대연, 김충모, 신영학, "전남지역에서 포획한 설치류의 한탄바이러스 감염에 대한 역학적 연구," 대한미생물 및 바이러스학회지, 제36권, 제3호, pp.205-210, 2006. https://doi.org/10.4167/jbv.2006.36.3.205
  10. 김효열, "신증후군 출혈열," 대한감염학회지, 제41권, 제6호, pp.323-332, 2009. https://doi.org/10.3947/ic.2009.41.6.323
  11. J. E. Smadel, "Epidemic hemorrhagic fever," Am J Public Health Nations Health, Vol.43, No.10, pp.1327-1330, 1953. https://doi.org/10.2105/AJPH.43.10.1327
  12. H. W. Lee, P. W. Lee, and K. M. Johnson, "Isolation of the etiologic agent of Korean Hemorrhagic fever," J Infect Dis, Vol.137, No.3, pp.298-308, 1978. https://doi.org/10.1093/infdis/137.3.298
  13. J. S. Lee, "Clinical features of hemorrhagic fever with renal syndrome in Korea," Kidney Int Suppl, No.35, pp.88-93, 1991.
  14. K. Ichimura, Y. Uchida, K. Arai, K. Nakazawa, J. Sasaki, and K. Kobayashi, "Afebrile scrub typhus(Tsutsugamushi disease) with acute respiratory distress syndrome," Intern Med, Vol.41, No.8, pp.667-670, 2002. https://doi.org/10.2169/internalmedicine.41.667
  15. D. M. Kim, H. L. Kim, C. Y. Park, S. H. Yoon, H. J. Song, and S. K. Shim, "Scrub Typhus," A prospective study of 76 cases, Infect Chemother, Vol.38, pp.186-191, 2006.
  16. A. J. McBride, D. A. Athanazio, M. G. Reis, and A. I. Ko, "Leptospirosis," Curr Open Infect Dis, Vol.18, No.5, pp.376-386, 2005. https://doi.org/10.1097/01.qco.0000178824.05715.2c
  17. S. Y. Seong and M. S. Choi, "Orientia tsutsugamushi infection," overview and immune reponses, Microbes and infection, Vol.3, No.1, pp.11-21, 2001. https://doi.org/10.1016/S1286-4579(00)01352-6
  18. J. W. Song, J. E. Lee, S. H. Kim, K. S. Park, and L. J. Baek, "Seroepidemiologic analysis of acute febrile illness in Korea during 1997-1998," J Bacteriol Virol, Vol.32, No.3, pp.263-267, 2002.
  19. S. S. Kweon, J. S. Choi, H. S. Lim, J. R. Kim, K. Y. Kim, S. Y. Ryu, H. S. Yoo, and O. Park, "Rapid increase of scrub typhus," South Korea, 2001-2006. Emerg infect Dis, Vol.15, No.7, pp.1127-1129, 2009. https://doi.org/10.3201/eid1507.080399
  20. N. Tachibana and A. Okayama, "Tsutsugamushi disease(scrub typhus)," Nippon Rinsho, Vol.65, No.3, pp.208-211, 2007.
  21. C. Cracco, C. Delafosse, L. Baril, Y. Lefort, C. Morelot, J. P. Derenne, F. Bricaire, and T. Similowski, "Multiple organ failure complicating probable scrub typhus," Clin Infect Dis, Vol.31, No.1, pp.191-192, 2000. https://doi.org/10.1086/313906
  22. 서일, 김일순, 전병율, 배용준, 정윤섭, "거제군 Scrub typhus 발생양상에 대한 역학적 조사", 한국역학회지, 제9권, 제1호, pp.17-27, 1997.
  23. 홍진희, 오진희, 김종현, 고대균, "쯔쯔가무시병에 발생한 급성신부전 1례", 소아과학회지, 제44권, 제4호, pp.464-468, 2001.
  24. M. Papadimitriou, "Hantavirus nephropathy," Kidney Int, Vol.48, No.3, pp.887-902, 1995. https://doi.org/10.1038/ki.1995.365
  25. 안용철, 황윤우, 김유석, 김주희, 조오현, 임채만, 우준희, "간 기능검사 결과 이상소견이 합병된 대유행 인플루엔자와 쯔쯔가무시병의 동시감염 환자 1예", 대한결핵 및 호흡기학회지, 제70권, 제3호, pp.247-250, 2011. https://doi.org/10.4046/trd.2011.70.3.247
  26. 심현선, 정홍량, 임청환, "초음파 검사에서 성인의 다낭성 간질환에 대한 고찰", 한국콘텐츠학회, 한국콘텐츠학회논문지, 제8권, 제10호, pp.217-223, 2008. https://doi.org/10.5392/JKCA.2008.8.10.217
  27. 박재일, 한성희, 조승철, 조용현, 홍상모, 이학현, "2000년대 초에 유행한 Orientia tsutsugamushi에 의한 간염," 대한간학회지, 제9권, 제3호, pp.198-205, 2003.
  28. 김선자, "2010년도 매개체전파질환 중복감염 보고사례 분석 결과," 주간 건강과 질병, 제26권, 제4호, pp.465-468, 2011.