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Increased Trend of Breast Cancer Mortality in Iran

  • Taghavi, Afsoon (Department of Pathology, Shahid Beheshti University of Medical Sciences) ;
  • Fazeli, Zeinab (Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences) ;
  • Vahedi, Mohsen (Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences) ;
  • Baghestani, Ahmad Reza (Department of Mathematics, Islamic Azad University) ;
  • Pourhoseingholi, Asma (Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences) ;
  • Barzegar, Farnoosh (Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences) ;
  • Pourhoseingholi, Mohamad Amin (Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences)
  • Published : 2012.01.31

Abstract

Background: Breast cancer is the most commonly diagnosed cancer in women worldwide In Iran, it ranks first among cancers diagnosed in women and is the fifth most common cause of death. The aim of this study was to present the mortality trends from breast cancer for Iranian women during a period of almost a decade, in order to provide update information regarding the likely future. Methods: We analyzed National death Statistic reported by the Iranian Ministry of Health and Medical Education from 1995 to 2004 to generate annual mortality rates/100,000, overall, by age group (<15, 15-49 and ${\geq}50$ years of age) and age standardized rate (ASR). Results: The age standardized mortality rate of breast cancer increased dramatically during these years from 1.40 to 3.52 per 100,000 and its mortality was increasing 151.4% for Iranian women, although it seemed that the rate leveled off from 2002 to 2004. Moreover the increasing rate was higher for those aged between 15-49 compared to age >50 years old. Conclusion: There is an increasing trend for breast cancer mortality in Iran. Thus, health education programs to rectify the lack of women awareness about breast cancer signs and effective screening are urgently needed.

References

  1. Ahmad O, Boschi Pinto C, Lopez AD, et al (2001). Age standardization of rates: a new WHO standard. Geneva, World Health Organization.
  2. Akbari ME (2008). Iran cancer report. Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Qom: Darolfekr.
  3. Autier P, Boniol M, Gavin A, et al (2011). Breast cancer mortality in neighbouring European countries with different levels of screening but similar access to treatment: trend analysis of WHO mortality database. BMJ, 28, 343-?.
  4. Botha JL, Bray F, Sankila R, et al (2003). Breast cancer incidence and mortality trends in 16 European countries. Eur J Cancer, 39, 1718-29. https://doi.org/10.1016/S0959-8049(03)00118-7
  5. Bulliard JL, La Vecchia C, Levi F (2006). Diverging trends in breast cancer mortality within Switzerland. Ann Oncol, 7, 57-9.
  6. Choi Y, Kim Y, Park SK, et al (2006). Age-Period-Cohort Analysis of Female Breast Cancer Mortality in Korea. Breast Cancer, 13, 266-71. https://doi.org/10.2325/jbcs.13.266
  7. Das B, Feuer EJ, Mariotto A (2005). Geographic association between mammography use and mortality reduction in the US. Cancer Causes Control, 16, 691-9. https://doi.org/10.1007/s10552-005-1991-x
  8. Elmore JG, Armstrong K, Lehman CD, et al (2005). Screening for breast cancer. JAMA, 293, 1245-56. https://doi.org/10.1001/jama.293.10.1245
  9. Forbes JF (1997). The incidence of breast cancer: the global burden, public health considerations. Semin Oncol, 24, 20-35.
  10. Fracheboud J, Otto SJ, Van Dijck JA, et al (2004). Decreased rates of advanced breast cancer due to mammography screening in The Netherlands. Br J Cancer, 91, 861-7. https://doi.org/10.1038/sj.bjc.6602075
  11. Harirchi I, Ebrahimi M, Zamani N, et al (2000). Breast cancer in Iran: a review of 903 case records. Public Health, 114, 143-5.
  12. Harirchi I, Karbakhsh M, Kashefi A, et al (2004). Breast cancer in Iran: results of a multi-center study. Asian Pac J Cancer Prev, 5, 24-7.
  13. Harirchi I, Kolahdoozan S, Karbakhsh M, et al (2011). Twenty years of breast cancer in Iran: downstaging without a formal screening program. Ann Oncol, 22, 93-7. https://doi.org/10.1093/annonc/mdq303
  14. He M, Guo Q, Hu G (2011). Reversed urban-rural differences in breast cancer mortality (China, 2002-2008). Breast Cancer Res Treat, 126, 231-4. https://doi.org/10.1007/s10549-010-1276-2
  15. Hery C, Ferlay JM, Boniol M, et al (2009). Quantification of changes in breast cancer incidence and mortality since 1990 in 35 countries with Caucasian-majority populations. Ann Oncol, 19, 1187-94. https://doi.org/10.1093/annonc/mdn025
  16. Hirte L, Nolte E, Bain C, et al (2007). Breast cancer mortality in Russia and Ukraine 1963-2002: an age-period-cohort analysis. Int J Epidemiol, 36, 900-6. https://doi.org/10.1093/ije/dym066
  17. Hoerger TJ, Ekwueme DU, Miller JW, et al (2011). Estimated Effects of the National Breast and Cervical Cancer Early Detection Program on Breast Cancer Mortality. Am J Prev Med, 40, 397-404. https://doi.org/10.1016/j.amepre.2010.12.017
  18. IARC (2002). Globocan 2002 Database. Mortality. Available at http://wwwdep. iarc.fr/.
  19. IzquierdoA, GispertR, Saladie F, et al (2008). Analysis of cancer incidence, survival and mortality according to the main tumoral localizations, 1985-2019: Breast cancer. Med Clin (Barc), 131, 50-2. https://doi.org/10.1016/S0025-7753(08)76433-9
  20. Katanoda K, Yako Suketomo H (2010). Comparison of Time Trends in Breast Cancer Mortality (1990-2006) in the World, from the WHO Mortality Database. Jpn J Clin Oncol, 40, 182-?. https://doi.org/10.1093/jjco/hyq003
  21. Kogevinas M, Pearce N, Susser M, et al (1997). Social inequalities and cancer. Lyon. IARC Scientific Publications no. 138.
  22. Kono A, Misumi J, Misumi J (2005). The time trend of breast cancer mortality in Japan. Arch Gynecol Obstet, 272, 187-90. https://doi.org/10.1007/s00404-004-0719-6
  23. Levi F, Bosetti C, Lucchini F, et al (2005). Monitoring the decrease in breast cancer mortality in Europe. Eur J Cancer Prev, 14, 497-502. https://doi.org/10.1097/00008469-200512000-00002
  24. Marks NF, Shinberg DS (1998). Socioeconomic status differences in hormone therapy. Am J Epidemiol, 148, 581-93. https://doi.org/10.1093/oxfordjournals.aje.a009684
  25. Mohagheghi MA, Mosavi-Jarrahi A, Malekzadeh R, et al (2009). Cancer Incidence in Tehran Metropolis: The First Report from the Tehran Population-Based Cancer Registry, 1998 - 2001. Arch Iran Med, 12, 15-23.
  26. Montazeri A, Vahdaninia M, Harirchi I, et al (2008). Breast cancer in Iran: need for greater women awareness of warning signs and effective screening methods. Asia Pac Fam Med, 7, 6-?. https://doi.org/10.1186/1447-056X-7-6
  27. Moore MA, Eser S, Igisinov N, et al (2010). Cancer epidemiology and control in North-Western and Central Asia - past, present and future. Asian Pac J Cancer Prev, 11, 17-32.
  28. Mousavi SM, Gouya MM, Ramazani R, et al (2009). Cancer incidence and mortality in Iran. Ann Oncol, 20, 556-63. https://doi.org/10.1093/annonc/mdn642
  29. Mousavi SM, Mohaghegghi MA, Mousavi-Jerrahi A, et al (2006). Burden of breast cancer in Iran: a study of the Tehran population based cancer registry. Asian Pac J Cancer Prev, 7, 571-4.
  30. Mousavi SM, Montazeri A, Mohagheghi MA, et al (2007). Breast cancer in Iran: an epidemiological review. Breast J, 13, 383-91. https://doi.org/10.1111/j.1524-4741.2007.00446.x
  31. Naghavi M (2002). Death report from 18 provinces in Iran. 1st edition. Ministry of Health and Medical Education, Tehran, Iran.
  32. Naghavi M (2003). Death report from 18 provinces in Iran. 1st edition. Ministry of Health and Medical Education, Tehran, Iran.
  33. Naghavi M (2004). Death report from 18 provinces in Iran. 1st edition. Ministry of Health and Medical Education, Tehran, Iran.
  34. Naghavi M, Abolhassani F, Pourmalek F, et al (2003). The burden of disease and injury in Iran 2003. Popul Health Metr, 15, 7-9.
  35. Park SK, Kim Y, Kang D, et al (2011). Risk factors and control strategies for the rapidly rising rate of breast cancer in Korea. J Breast Cancer, 14, 79-87. https://doi.org/10.4048/jbc.2011.14.2.79
  36. Parkin DM, Bray F, Ferlay J, et al (2005). Global cancer statistics, 2002. CA Cancer J Clin, 55, 74-108. https://doi.org/10.3322/canjclin.55.2.74
  37. Parkin DM, Whelan SL, Ferlay J, et al (1997). Cancer incidence in five continents, vol. VII. Lyon. IARC Scientific Publications no. 143.
  38. Sadjadi A, Nouraie M, Mohagheghi MA, et al (2005). Cancer occurrence in Iran in 2002, an international perspective. Asian Pac J Cancer Prev, 6, 359-63.
  39. Shamsa AZ, Mohagheghi MA (2002). Final report of the National project for cancer registry. Islamic Republic of Iran.
  40. Threlfall AG, Collins S, Woodman CB (2003). Impact of NHS breast screening on advanced disease and mortality from breast cancer in the North West of England. Br J Cancer, 89, 77-80. https://doi.org/10.1038/sj.bjc.6600842
  41. U.S. Cancer Statistics Working Group (2010). U.S. Cancer Statistics: 2005 Incidence and Mortality. Atlanta GA: USDHHS, CDC and National Cancer Institute, www.cdc.gov/uscs.
  42. Wilson CM, Tobin S, Young RC (2004). The exploding worldwide cancer burden: the impact of cancer on women. Int J Gynecol Cancer, 14, 1-11.
  43. World Health Organization (2009). Mortality database. WHO, , 2-6.
  44. World Health Organization: Cancer (2008). [http://www.who.int/mediacentre/factsheets/fs297/en]. accessed 30.07.
  45. Yavari P, Pourhoseingholi MA (2007). Socioeconomic factors association with knowledge and practice of breast selfexamination among Iranian women. Asian Pac J Cancer Prev, 8, 618-22.
  46. W, Shu XO, McLaughlin JK, et al (1993). Occupational physical activity and the incidence of cancer of the breast, corpus uteri, and ovary in Shanghai. Cancer, 71, 3620-4. https://doi.org/10.1002/1097-0142(19930601)71:11<3620::AID-CNCR2820711125>3.0.CO;2-S

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