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유근피 추출물의 생리활성

Physiological Activities of $Ulmus$ $pumila$ L. Extracts

  • 정광열 (대구한의대학교 한방식품조리영양학부) ;
  • 김미림 (대구한의대학교 한방식품조리영양학부)
  • Jeong, Kwang-Yeol (Department of Faculty of Herbal Cuisine and Nutrition, Daegu Hanny University) ;
  • Kim, Mi-Lim (Department of Faculty of Herbal Cuisine and Nutrition, Daegu Hanny University)
  • 투고 : 2011.09.28
  • 심사 : 2012.02.03
  • 발행 : 2012.02.28

초록

본 연구는 느릅나무과(Ulmaceae)에 속하는 유근피(Ulmuspumila L.)추출물을 기능성식품에 활용하기 위하여 폴리페놀 함량, 항산화능 및 암세포 증식 억제능의 기능성에 대하여 조사하였다. 물 추출물 및 에탄올 추출물의 수율은 각각 12.7%와 12.0%였으며, polyphenol 화합물의 함량은 $623.5{\pm}2.4$ mg/100g 및 $710.5{\pm}2.1$ mg/100g이었고, 전자공여능은 농도에 비례하여 높아, 1,000 ppm에서 물추출물은 76%, 에탄올 추출물은 64%로 물 추출물이 에탄올 추출물 보다 높았다. SOD유사활성능은 전 농도에서 물 추출물이 에탄올 추출물보다 높아 1,000 ppm에서는 물 추출물이 53%, 에탄올 추출물이 38%이었고, 아질산염 소거능은 1,000 ppm에서 에탄올 추출물이 47%, 물 추출물이 43%로 에탄올 추출물이 물 추출물보다 다소 높았다. 항암성은 MDA cell에서 1,000 ppm의 경우 물 추출물은 62%, 에탄올 추출물은 42%이었으며, A549 cell에서 1,000 ppm의 경우 물 추출물은 60%, 에탄올 추출물은 45%로 물 추출물이 에탄올 추출물보다 암세포증식 억제력이 월등히 높았다.

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피인용 문헌

  1. Effect of extract temperature and duration on antioxidant activity and sensory characteristics of Ulmus pumila bark extract vol.23, pp.7, 2016, https://doi.org/10.11002/kjfp.2016.23.7.995
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  3. Antioxidative Activity of Feral Haw (Crataegus pinnatifida BUNGE) Seed Extracts Using Various Solvents vol.30, pp.1, 2014, https://doi.org/10.9724/kfcs.2014.30.1.033
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  12. Antioxidant and α-Glucosidase Inhibition Activities of Solvent Fractions from Methanolic Extract of Sericea Lespedeza (Lespedeza cuneata G. Don) vol.41, pp.11, 2012, https://doi.org/10.3746/jkfn.2012.41.11.1508
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