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Antiobesity Effect of the Cucubita moschata Duch Extracts in 3T3-L1 Adipocyets

지방세포에서 늙은호박(Cucubita moschata Duch) 추출물의 항비만 효과

  • Received : 2011.09.02
  • Accepted : 2012.01.06
  • Published : 2012.02.28

Abstract

The anti-obesity activity of the $Cucubita$ $moschata$ Duch. extracts was investigated. The inhibitory effect on triglyceride accumulation was shown in 3T3-L1 preadipocyte. The lipid accumulation of the ethanol extract in 5 mg/mL concentration was shown to be 75.4%, where as that of water extract was shown to be 85.2%. The survival rate of the cell in the viability test was shown to be 86.5% in the 0.5-5 mg/mL concentration. Total polyphenol content was highest in the water extract($46.54{\pm}0.02$ mg). These results suggest that $Cucubita$ $moschata$ Duch. extracts have a potential as anti-obesity material by reducing the lipid accumulation.

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