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Occurrence and Prognosis for the Thrombosis in the Drug-Eluting Stents and Bare-Metal Stents

약물 용출 스텐트와 일반 금속 스텐트에서 혈전증에 대한 발생과 예후

  • 김인수 (동신대학교 방사선학과) ;
  • 최남길 (동신대학교 방사선학과) ;
  • 장성주 (동신대학교 방사선학과) ;
  • 한재복 (동신대학교 방사선학과) ;
  • 장영일 (광양보건대학교 방사선과)
  • Received : 2012.04.27
  • Accepted : 2012.05.31
  • Published : 2012.07.28

Abstract

Drug-eluting stents (DES) have significantly reduced in-stent restenosis, compared to bare-metal stents (BMS). However, there remains concern for the increased risk of stent thrombosis (ST) associated with DES. The present study sought to evaluate the incidence, clinical characteristics and outcome of ST in patients with acute myocardial infarction (MI) during a 1-year follow-up. 80 patients who developed ST were divided into 2 groups according to stent type: group I (DES-ST, n = 57 ) and group II (BMS-ST, n = 23 ). There were no differences between group I and II in the overall incidence of ST (2.7% vs. 4.3%, p=0.064) and in the incidence of each type of ST: acute ST (8.8% vs. 2.3%), subacute ST (50.9% vs. 60.9%), late ST (19.3% vs. 8.7%), and very late ST (21.1% vs. 17.4%) (p=0.605). Predictors of 1-year mortality were the occurrence of ST (OR 8.12, 95% CI 2.83-23.61, p<0.001), left ventricular ejection fraction<40% (OR 6.41, 95% CI 2.42-16.96, p<0.001), and age${\geq}$75 years (OR 4.98, 95% CI 1.95-12.74, p=0.001).

Keywords

Drug-eluting stents;Stent thrombosis;Percutaneous Coronary Intervention

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