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A Study on Biological Activities of Opuntia humifusa Cladode Extracts

손바닥 선인장 (Opuntia humifusa) 줄기 추출물의 생리활성

  • Yoon, Min-Sun (Department of Food Science & Biotechnology, Chonbuk National University) ;
  • Yoo, Jae-Soo (Department of Food Science & Biotechnology, Chonbuk National University) ;
  • Lee, Keun-Kwang (Department of Beauty Arts, Koguryeo College) ;
  • Kim, Myung-Kon (Department of Food Science & Biotechnology, Chonbuk National University)
  • Received : 2011.10.14
  • Accepted : 2012.04.02
  • Published : 2012.06.30

Abstract

Biological activities of the hot water and ethanol extracts from Opuntia humifusa cladodes were investigated. 1,1-diphenyl-2-picryl hadrazyl (DPPH) electron donating ability of hot water and ethanol extracts was 79.07 and 82.54%, respectively. Hot water extract generally showed better cytotoxic activity than ethanol extract against each cell line. HeLa and AGS cell lines treated with hot water extract had more than 50% cytotoxic activities. Based on the antimicrobial activities against four microbial strains, both extracts inhibited growth of Staphylococcus aureus KCCM 11593, whereas affected cell growth of three other microorganisms, Escherichia coli (KCCM 11234), Pseudomonas aeruginosa (ATCC 27853), and Salmonella typhimurium (ATCC 11862), in proportion to the concentration of extracts. The inflammatory activities against hot water extract (34.31%) showed higher than that of ethanol extract (25.59%). The effect of extracts on 3T3-L1 preadipocytes differentiation showed that differentiation of treated group with 80 and 100 ${\mu}g/mL$ of hot and ethanol extracts were increased more than treated group with isobutyl methyl xanthine (IBMX) + dexamethasone. These results indicate that the O. humifusa cladodes extracts can be used as a functional material due to their effective biological activities.

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  3. Flow behaviors of fruit and stem extracts from Korean cactus (Opuntia humifusa) vol.23, pp.4, 2014, https://doi.org/10.1007/s10068-014-0151-z
  4. Quality Characteristics and Antioxidant Activity of Prickly Pear Cactus Cladodes vol.44, pp.3, 2015, https://doi.org/10.3746/jkfn.2015.44.3.356
  5. Antioxidant and anti-inflammatory activities of Opuntia ficus-indica and Opuntia humifusa fruits ethanol extracts vol.25, pp.5, 2018, https://doi.org/10.11002/kjfp.2018.25.5.586