DOI QR코드

DOI QR Code

Gynecological Malignancies: Epidemiological Characteristics of the Patients in a Tertiary Care Hospital in India

  • Sarkar, Madhutandra (Department of Community Medicine, Chettinad Hospital and Research Institute) ;
  • Konar, Hiralal (Department of Obstetrics and Gynecology, Nilratan Sircar Medical College and Hospital) ;
  • Raut, D.K. (Department of Community Medicine, VM Medical College and Safdarjung Hospital)
  • Published : 2012.06.30

Abstract

Background: This cross-sectional observational study was undertaken to identify the epidemiological characteristics of patients with gynecological malignancies in India, in relation to gynecological cancer risk. Methods: In the gynecology out-patient clinic of a tertiary care hospital in Kolkata, India, the patients with suggestive symptoms of gynecological malignancies were screened. One hundred thirteen patients with histopathologically confirmed gynecological malignancies were interviewed. Results: More than two-thirds of the cases (69.0%) occurred in the age range of 35-64 years and the same proportion of patients was from rural areas. Almost all the patients were "ever-married" (96.5%). More than half (54.9%) were illiterate/just literate. Nearly two-thirds (64.6%) were parity 3 or higher. Among the 18 patients with history of multiple sexual partners of the husband, 94.4% (17) were suffering from cervical malignancy, along with all the 3 patients with history of STD syndromes (sexually transmitted diseases) of their husbands. No one had given a history of condom use by her husband. Most of the patients (91.1%) used old / reused cloth pieces during menstruation. Conclusions: There is a need to increase awareness among women and the broader community about different epidemiological factors that may be responsible for increased risk of gynecological malignancies.

Keywords

Gynecological malignancies;women;epidemiological characteristics;cancer risk;awareness;India

References

  1. Ayinde OA, Omigbodun AO, Ilesanmi AO (2004). Awareness of Cervical Cancer, Papanicolaou's Smear and Its Utilisation among Female Undergraduates in Ibadan. Afr J Reprod Health, 8, 68-80. https://doi.org/10.2307/3583394
  2. Berek JS (2002). Novak's Gynecology, Thirteenth Edition. Philadelphia: Lippincott Williams & Wilkins.
  3. Chhabra S, Sonak M, Prem V, Sharma S (2002). Gynaecological malignancies in a rural institute in India. J Obstet Gynaecol, 22, 426-9. https://doi.org/10.1080/01443610220141434
  4. Daly C, Fitzpatrick R, Murphy H (1989). Ovarian cancer in a county hospital. Ir Med J, 82, 60-1.
  5. Dasgupta A, Sarkar M (2008). A study on reproductive tract infections among married women in the reproductive age group (15-45 years) in a slum of Kolkata. J Obstet Gynecol India, 58, 518-22.
  6. Dasgupta A, Sarkar M (2008). Menstrual hygiene: how hygienic is the adolescent girl? Indian J Community Med, 33, 77-80. https://doi.org/10.4103/0970-0218.40872
  7. Dutta DC (2003). Text Book of Gynaecology including contraception, Fourth Edition. Calcutta: New Central Book Agency (P) Ltd.
  8. Department of Health, Social Services & Public Safety, Northern Ireland (2002). Epidemiology of Gynaecological Cancer in Northern Ireland. Guidance for the Management of Gynaecological Cancer. Belfast: DHSSPS.
  9. De Nooijer J, Lechner L, De Vries H (2002). Early detection of cancer: knowledge and behavior among Dutch adults. Cancer Detect Prev, 26, 362-9. https://doi.org/10.1016/S0361-090X(02)00121-6
  10. Ferlay J, Bray F, Pisani P, Parkin DM (2004). GLOBOCAN 2002: Cancer Incidence, Mortality and Prevalence Worldwide. IARC Cancer Base No. 5, version 2.0. Lyon: IARC Press.
  11. Grimes DA, Economy KE (1995). Primary prevention of gynecologic cancers. Am J Obstet Gynecol, 172, 227-35. https://doi.org/10.1016/0002-9378(95)90125-6
  12. Juneja A, Sehgal A, Mitra AB, Pandey A (2003). A survey on risk factors associated with cervical cancer. Indian J Cancer, 40, 15-22.
  13. Kidanto HL, Kilewo CD, Moshiro C (2002). Cancer of the cervix: knowledge and attitudes of female patients admitted at Muhimbili National Hospital, Dar es Salaam. East Afr Med J, 79, 467-75.
  14. Laurvick CL, Semmens JB, Holman CD, Leung YC (2003). Ovarian cancer in Western Australia (1982-98): incidence, mortality and survival. Aust N Z J Public Health, 27, 588-95. https://doi.org/10.1111/j.1467-842X.2003.tb00604.x
  15. Leydon GM, Boulton M, Moynihan C, et al (2000). Cancer patients' information needs and information seeking behaviour: in depth interview study. BMJ, 320, 909-13. https://doi.org/10.1136/bmj.320.7239.909
  16. Malik IA (2002). A prospective study of clinico-pathological features of epithelial ovarian cancer in Pakistan. J Pak Med Assoc, 52, 155-8.
  17. Mogren I, Stenlund H, Hogberg U (2001). Long-term impact of reproductive factors on the risk of cervical, endometrial, ovarian and breast cancer. Acta Oncol, 40, 849-54. https://doi.org/10.1080/02841860152703481
  18. Nigam PK, Jain A, Goyal P, Chitra R (2005). Role of heat stable fraction of alkaline phosphatase as an adjunct to CA 125 in monitoring patients of epithelial ovarian carcinoma. Indian J Clin Biochem, 20, 43-7.
  19. Nasreen F (2002). Pattern of gynaecological malignancies in tertiary hospital. J Postgrad Med Inst, 16, 215-20.
  20. Nkyekyer K (2000). Pattern of gynaecological cancers in Ghana. East Afr Med J, 77, 534-8.
  21. Odukogbe AA, Adebamowo CA, Ola B, et al (2004). Ovarian cancer in Ibadan: characteristics and management. J Obstet Gynaecol, 24, 294-7. https://doi.org/10.1080/01443610410001660904
  22. Rashid S, Sarwar G, Ali A (1998). A Clinico-Pathological Study of Ovarian Cancer. Mother & Child, 36, 117-25.
  23. Sarkar M, Konar H, Raut DK (2011). Knowledge and health careseeking behavior in relation to gynecological malignancies in India: A study of the patients with gynecological malignancies in a tertiary care hospital of Kolkata. J Cancer Educ, 26, 348-54. https://doi.org/10.1007/s13187-010-0168-9
  24. Sarkar M, Konar H, Raut DK (2010). Symptomatology of gynecological malignancies: Experiences in the Gynecology Out-Patient Clinic of a tertiary care hospital in Kolkata, India. Asian Pac J Cancer Prev, 11, 785-91.
  25. Senate Community Affairs References Committee, Commonwealth of Australia (2006). Inquiry into gynaecological cancers in Australia. Breaking the silence: a national voice for gynaecological cancers. Canberra: The Senate Standing Committee on Community Affairs.
  26. Sankaranarayanan R, Ferlay J (2006). Worldwide burden of gynaecological cancer: The size of the problem. Best Pract Res Clin Obstet Gynaecol, 20, 207-25. https://doi.org/10.1016/j.bpobgyn.2005.10.007
  27. Sharma R, Maheshwari V, Aftab M, Das BC (2005). Role of different epidemiological factors, colposcopy and cytology in the screening of cervical cancer in symptomatic patients. Indian J Med Res, 121, 109-10.
  28. Surveillance, Epidemiology Branch, Centre for Health Protection, Department of Health, Government of the Hong Kong Special Administrative Region (2004). Topical Health Report No. 4. Prevention and Screening of Cervical Cancer. Hong Kong: Department of Health.
  29. Siyal AR, Shaikh SM, Balouch R, Surahio AW (1999). Gynaecological cancer: A histopathological experiences at Chandka Medical College and Hospital Larkana. Med Channel, 5, 15-9.
  30. Trope CG, Makar AP (1991). Epidemiology, etiology, screening, prevention, and diagnosis in female genital cancer. Curr Opin Oncol, 3, 908-19. https://doi.org/10.1097/00001622-199110000-00016
  31. Were EO, Buziba NG (2001). Presentation and health care seeking behaviour of patients with cervical cancer seen at Moi Teaching and Referral Hospital, Eldoret, Kenya. East Afr Med J, 78, 55-9.
  32. Walboomers JM, Jacobs MV, Manos MM, et al (1999). Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol, 189, 12-9. https://doi.org/10.1002/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F
  33. World Health Organization (1986). Control of cancer of the cervix uteri. A WHO Meeting. Bull WHO, 64, 607-18.

Cited by

  1. Clinico-pathological Features of Gynecological Malignancies in a Tertiary Care Hospital in Eastern India: Importance of Strengthening Primary Health Care in Prevention and Early Detection vol.14, pp.6, 2013, https://doi.org/10.7314/APJCP.2013.14.6.3541
  2. Roles for Paraoxonase but not Ceruloplasmin in Peritoneal Washing Fluid in Differential Diagnosis of Gynecologic Pathologies vol.15, pp.15, 2014, https://doi.org/10.7314/APJCP.2014.15.15.6233
  3. Clinical Impact of De-Regulated Notch-1 and Notch-3 in the Development and Progression of HPV-Associated Different Histological Subtypes of Precancerous and Cancerous Lesions of Human Uterine Cervix vol.9, pp.6, 2014, https://doi.org/10.1371/journal.pone.0098642