The study of utility about magnetic resonance elastography for measurements of liver stiffness : the comparisons of ADC value & T2 weighted image

간 경화도 측정을 위한 3.0T 자기공명 탄성계수 영상의 유용성에 대한 고찰 : 확산계수 영상 및 T2 강조 영상과의 비교

  • Kim, Sang-Woo (Department of Radiology, Konkuk University Medical Center) ;
  • Kang, Chung-Hwan (Department of Radiology, Konkuk University Medical Center) ;
  • Kim, Sung-Ho (Department of Radiology, Konkuk University Medical Center) ;
  • Kim, Kyung-Soo (Department of Radiology, Konkuk University Medical Center) ;
  • Kim, Soon-Bae (Department of Radiology, Konkuk University Medical Center)
  • 김상우 (건국대학교병원 영상의학과 MRI실) ;
  • 강충환 (건국대학교병원 영상의학과 MRI실) ;
  • 김성호 (건국대학교병원 영상의학과 MRI실) ;
  • 김경수 (건국대학교병원 영상의학과 MRI실) ;
  • 김순배 (건국대학교병원 영상의학과 MRI실)
  • Received : 2012.02.07
  • Accepted : 2012.03.30
  • Published : 2012.03.31

Abstract

The purpose of this study is to evaluate the mutual relations by measuring SNR from T2 weighted image and ADC values on the basis of the stiffness values from liver tissues. This study was conducted that total 37 people(23 of males and 11 of females) were taken the liver MRI examination and average age was $54.5{\pm}12.7$ years old. The equipment was MAGNETOM Skyra 3.0T (SIEMENS, Erlangen, Germany) and 32 channel body-array coil. The examination were conducted with HASTE T2 weighted image by axial plane, Spin-echo EPI (echo planner image) DWI (b-value = 800) and Magnetic resonance elastography. The ROIs (region of interest: 200-300 $mm^2$) were established on the basis of the first axial stiffness image corresponded 95% confidence interval from axial stiffness image and then were measured values. After drawing the grid lines, signals were measured SNR from T2 weighted image and ADC values on the same locations that were analysed other 3 planes respectively. The results were showed correlation (0.057) that were increased to SNR from T2 weighted image by increasing stiffness value that no significant difference statistically p = 0.003. Other results were showed correlations (-0.301) that were decreased to ADC values by increasing stiffness values that no significant difference statistically p = 0.088. In the 3.0T equipment, the results may be error in much the same fashion as the 1.5T from ADC values by evaluation of fibrosis stage. However, Magnetic resonance elastography would be useful method that is used to diagnose exactly liver fibrosis stages in the 3.0T.