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The effects of Germanium biotite on the adsorptive and inhibition of growth abilities against E. coli and Salmonella spp. in vitro

게르마늄 흑운모의 시험관 내에서의 E. coli와 Salmonella spp.에 대한 흡착력 및 성장 억제 효능 평가

  • Jung, Myunghwan (Department of Infectious Diseases, College of Veterinary Medicine and Brain Korea 21 Program for Veterinary Science, Seoul National University) ;
  • Cha, Seung Bin (Department of Infectious Diseases, College of Veterinary Medicine and Brain Korea 21 Program for Veterinary Science, Seoul National University) ;
  • Shin, Seung Won (Department of Infectious Diseases, College of Veterinary Medicine and Brain Korea 21 Program for Veterinary Science, Seoul National University) ;
  • Lee, Won-Jung (Department of Infectious Diseases, College of Veterinary Medicine and Brain Korea 21 Program for Veterinary Science, Seoul National University) ;
  • Shin, Min-Kyoung (Department of Infectious Diseases, College of Veterinary Medicine and Brain Korea 21 Program for Veterinary Science, Seoul National University) ;
  • Yoo, Anna (Department of Infectious Diseases, College of Veterinary Medicine and Brain Korea 21 Program for Veterinary Science, Seoul National University) ;
  • Yoo, Han Sang (Department of Infectious Diseases, College of Veterinary Medicine and Brain Korea 21 Program for Veterinary Science, Seoul National University)
  • 정명환 (서울대학교 수의과대학, BK21 수의과학인력양성 사업단) ;
  • 차승빈 (서울대학교 수의과대학, BK21 수의과학인력양성 사업단) ;
  • 신승원 (서울대학교 수의과대학, BK21 수의과학인력양성 사업단) ;
  • 이원정 (서울대학교 수의과대학, BK21 수의과학인력양성 사업단) ;
  • 신민경 (서울대학교 수의과대학, BK21 수의과학인력양성 사업단) ;
  • 유안나 (서울대학교 수의과대학, BK21 수의과학인력양성 사업단) ;
  • 유한상 (서울대학교 수의과대학, BK21 수의과학인력양성 사업단)
  • Received : 2011.10.20
  • Accepted : 2012.01.17
  • Published : 2012.03.30

Abstract

Germanium biotite, a natural mineral, has been used as a feed supplement to reinforce innate immune ability. The aim of the present study was to evaluate the effects of germanium biotite on the adsorptive and inhibition of growth abilities against Escherichia (E.) coli and Salmonella spp. in vitro. Two strains of enterotoxigenic E. coli and four strains of two Salmonella serotypes (Salmonella Derby and Salmonella Typhimurium), major bacterial diarrheal pathogens, were used for this experiment. The absorptive ability of germanium biotite against most Salmonella used in present experiment was observed weakly. The germanium biotite, however, showed significant effect of bacterial growth inhibition in most experiment bacteria. These results suggest that the use of the germanium biotite as feed supplement could alleviate diarrhea following inhibition of bacteria growth. It is also presumed that antibiotics usage for farm animals, considered as causes of antibiotic residue in meat and emerging antibiotic resistance, could be reduced through the use of germanium biotite as a feed supplement, in place of antibiotics used for the prevention of diarrhea.

Acknowledgement

Supported by : 농림수산식품기술기획평가원