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Effects of vitamin C on oxidative status in pigs anesthetized with isoflurane

  • Lee, Jae Yeon (College of Veterinary Medicine, Chungnam National University) ;
  • Kim, Myung Cheol (College of Veterinary Medicine, Chungnam National University)
  • Received : 2012.04.27
  • Accepted : 2012.06.20
  • Published : 2012.09.30

Abstract

This study investigated the effects of vitamin C on oxidative stress induced by volatile anesthetics in pigs. One group of pigs was used as an anesthesia control group (group 1), and they were anesthetized with isoflurane in oxygen and saline (0.9% NaCl) was injected intravenously. The other group (group 2) was anesthetized with isoflurane and injected intravenously with vitamin C. Total oxidant status, total antioxidant status, and the oxidative stress index in group 2 were significantly different compared with those in group 1. The results showed that intravenous administration of vitamin C decreased oxidative stress during isoflurane anesthesia in pigs.

Acknowledgement

Supported by : National Research Foundation of Korea(NRF)