Analysis change in Bone Mineral Density before and after Kidney Transplant in Renal Failure Patient

신부전환자의 신장이식 전후 골밀도변화 분석

  • 박형후 (고신대학교 대학원 보건과학과) ;
  • 옥치상 (고신대학교 대학원 보건과학과) ;
  • 박영인 (고신대학교 대학원 보건과학과) ;
  • 이진수 (부산가톨릭대학교 보건과학대학 대학원 방사선학과) ;
  • 김창수 (부산가톨릭대학교 보건과학대학 대학원 방사선학과)
  • Received : 2012.06.01
  • Accepted : 2012.08.10
  • Published : 2012.09.28


Disease, such as osteopenia, osteoporosis, etc caused by reduced bone density are common to women after menopause and as the social medical cost increases due to osteoporosis fractures the medical interest in bone density reduction has increased. The bone density reduction is observed even for renal failure patients, due to their decreased ability to synthesize vitamin D which leads to bone fibrosis because of deficiency in calcium absorption. Thus renal failure patients not only suffer from kidney dysfunction, but also are exposed to complications, such as osteoporosis, due to reduced bone density. This research observed the change in bone density of patients receiving renal failure treatment and analyzed the change in bone density before and after kidney transplantations. Subjects were 214 renal failure patients at the department of nephrology Busan B General Hospital. The change in bone density was studied for subjects with and without kidney transplantation according to their age and sex. The research showed improvement or maintenance of bone density for subjects that received kidney transplantation, but showed a tendency of consistent decrease in bone density for subjects without kidney transplantation. Kidney transplantation can be considered as the best cure for renal failure patients, and this researched confirmed that bone density can be improved through kidney transplantation. Thus, this study can also be used as data for preventing complications due to renal failures.


Renal Failure;Bone Mineral Density;T-score;Kidney Transplants


  1. 최명애, 이경숙, 정재심, 안경주, 채영란, 신기수, 전미양, 최정안, 조미경, 이경숙, 병태 생리학, 계축문화사, pp.109-130, pp.379-397, 2010.
  2. Available at: Accessed February 10, 2012.
  3. 류익태, 신부전증 치료 생활요법, 태웅출판사, pp.4-12, 1991.
  4. 대한골다공증학회, 골밀도측정가이드, 청운출판사, pp.5-25, 2009.
  5. 고석봉, 이광희, 곽양수, 이두진, 박윤기, 이승호, "폐경기 증상과 양측 난소제게술이 골밀도에 미치는 영향", 대한산부인과학회지, 제37권, 제10호, pp.2037-2046, 1994.
  6. 장준섭, 강군순, 박희완, 한명훈, "정량적 전산화 단층촬영을 이용한 요추부의 골밀도 측정", 대한정형외과학회지, 제25권, 제1호, pp.262-269, 1990.
  7. Y. I. Kim, J. H. Park, J. S. Lee, J. W. Kim, S. O. Yang, and D. J. Jeon, "Prevalence and risk factors of the osteoporosis of perimenopausal women in the community population," Korean J Med, Vol.62, pp.11-24, 2002.
  8. H. K. Yoon, S. W. Kim, C. H. Yim, H. Y. Chung, H. J. Oh, and K. O. Han, "Metabolic characteristic and prevalence of osteoporosis among women in Tae-An area," J Korean Med Sci, Vol.16, pp.323-327, 2001.
  9. C. H. Kim, Y. I. Kim, C. S. Choi, J. Y. Park, M. S. Lee, and S. I. Lee, "Prevalence and risk factors of low quantitative ultrasound values of calcaneus in Korean elderly women," Ultrasound and Med Biol, Vol.26, pp.35-40, 2000.
  10. 모은희, 조정근, 이상호, 임청환, 최지원, "40세 이후 남성의 골밀도 관련 요인과 골다공증의 유병률", 한국콘텐츠학회지, 제8권, 제9호, pp.242-247, 2008.
  11. 김기범, 안성민, 이귀원, 김성철, "정량적 전산화 단층촬영법과 정량적 초음파법에 의한 골밀도 측정비교", 한국콘텐츠학회지, 제11권, 제8호, pp.198-202, 2011.
  12. 최희정, 이득주, "여성에서 연령에 따른 척추 골밀도의 변화와 누적 골 소실률", 대한폐경학회지, 제9권, 제2호, pp.171-177, 2003.
  13. 정용준, 박정원, 이근미, 정승필, " 폐경 전 여성의 골밀도와 관련된 요인", 가정의학회지, 제22권, 제3호, pp.263-270, 2001.
  14. H. K. Rho, E. S. Lee, and H. M. Park, Perception level of Vitamin D and calcium on osteoporosis treatment, The Journal of Korean society of Menopause, Vol.14, No.2, pp.115-129, 2008.
  15. Ethel S. Siris, Ya-Ting Chen, T. A. Abbott, E. Barrett-Connor, P. D. Miller, L. E. Wehren, and M. L. Berger, "Bone mineral density thresholds for pharmacological intervention to prevent fractures," Archives of Internal Medicine, Vol.164, No.10, pp.1108-1112, 2004.
  16. R. C. Hamdy, S. M. Petak, and I. Lenchik, "Which central dual X-ray absorptiometry skeletal sites and regions of interest should be used to determine the diagnosis of osteoporosis," J Clinical Densitometry, Vol.5(Supplement), pp.11-17, 2002.
  17. 변영순, 신공범, 골다공증이란 무엇인가, 도서출판 정담, pp.57-64, 1992.