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Antioxidative Activities and Whitening Effects of Solvent Fraction from Prunus davidiana (Carriere) Franch. Fruit

산복사나무(Prunus davidiana (Carriere) Franch.) 열매 분획 추출물의 항산화 및 미백 효능

  • Kim, Won Baek (Dept. of Food Science and Nutrition, Pusan National University) ;
  • Park, So Hae (Dept. of Food Science and Nutrition, Pusan National University) ;
  • Hwang, Hye Sun (Dept. of Food Science and Nutrition, Pusan National University) ;
  • Woo, Jung Yoon (Dept. of Food Science and Nutrition, Pusan National University) ;
  • Lee, Hye Ryun (Dept. of Biomaterial Science, Pusan National University) ;
  • Hwang, Dae Youn (Dept. of Biomaterial Science, Pusan National University) ;
  • Choi, Ji Hye (Dept. of Food and Life Science, Inje University) ;
  • Lee, Heeseob (Dept. of Food Science and Nutrition, Pusan National University)
  • 김원백 (부산대학교 식품영양학과) ;
  • 박소해 (부산대학교 식품영양학과) ;
  • 황혜선 (부산대학교 식품영양학과) ;
  • 우정윤 (부산대학교 식품영양학과) ;
  • 이혜련 (부산대학교 바이오소재과학과) ;
  • 황대연 (부산대학교 바이오소재과학과) ;
  • 최지혜 (인제대학교 식품생명과학부) ;
  • 이희섭 (부산대학교 식품영양학과)
  • Received : 2012.06.12
  • Accepted : 2012.09.12
  • Published : 2012.10.31

Abstract

In this study, methanol extract and its organic solvent fractions were prepared from Prunus davidiana (Carriere) Franch. fruit. Antioxidative activities, polyphenolic and flavonoid contents, and tyrosinase inhibitory activities were evaluated. Among the fractions, ethyl acetate fraction showed the highest antioxidative activity with $IC_{50}$ values of 5.8 ${\mu}g/mL$ and 88.1 ${\mu}g/mL$ for DPPH radical and nitrite scavenging, respectively, which were comparable to those of ascorbic acid. Further, total flavonoid and polyphenolic contents were highest in the ethyl acetate fraction with $IC_{50}$ values of 244.5 mg/g and 210.2 mg/g, respectively. $IC_{50}$ values for tyrosinase inhibitory activity were 0.310 mg/mL and 0.329 mg/mL for the ethyl acetate and n-butanol fractions, respectively. Based on these results, it is suggested that the ethyl acetate fraction of Prunus davidiana (Carriere) Franch. fruit could be used as a functional material in the food and pharmaceutical industries.

Acknowledgement

Supported by : 부산대학교

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