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Clinical Outcomes of Stent Thrombosis after Drug-Eluting Coronary Stent Implantation

약물방출 관상동맥 스텐트 시술 후 스텐트 혈전증 발생 환자의 임상경과

  • 김인수 (동신대학교 방사선학과) ;
  • 정명호 (전남대학교병원 심혈관센터) ;
  • 한재복 (동신대학교 방사선학과) ;
  • 장영일 (광양보건대학교 방사선과) ;
  • 장성주 (동신대학교 방사선학과)
  • Received : 2013.10.07
  • Accepted : 2013.12.02
  • Published : 2013.12.28

Abstract

Stent thrombosis after successful drug-eluting stent(DES) implantation has been reported in around 1% of patients in clinical trials. However, the increased risk of ST associated with DES remains a matter of concern. From 1 June 2003 to 30 June 2013, we investigated clinical characteristics, in-hospital outcomes in 10,273 patients who underwent percutaneous coronary intervention in the Heart Center of CNUH. Overall incidence of ST was 1.30% (134 patients). The incidence of ST according to the stent generations and the timing of ST (n=total, early vs. late vs. very late) were 0.79% (n=81, 26 vs. 12 vs. 43) in first-generation, 0.38% (n=39, 21 vs. 9 vs. 9) in second-generation and 0.14% (n=14, 8 vs 3 vs. 3) in third-generation, (p=0.70). The mortality from ST was significantly higher in early ST group compared to the late and very late ST groups (18.2% vs. 8.3% vs. 3.6%, p=0.042). Overall incidence of ST after DES implantation was 1.30% (134 patients). The in-hospital mortality was significantly higher in early ST group compared to the late and very late ST groups.

Keywords

Drug-eluting Stents;Stent Thrombosis;Percutaneous Coronary Intervention

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